Department of Veterinary Sciences, University of Messina, Polo Universitario dell'Annunziata, Messina, Italy.
Department of Biomedical, Dental, Morphological and Functional Images, Specializing in Sports and Exercise Medicine, University of Messina, Messina, Italy.
J Equine Vet Sci. 2020 May;88:102986. doi: 10.1016/j.jevs.2020.102986. Epub 2020 Mar 6.
Physiological and hematochemical changes associated with exercise have been extensively investigated in equine species. It is known that stress elevates circulating levels of acute phase proteins (APPs). This survey evaluated whether horses trained with different training programs exhibit changes in APP levels after exercise event. Twenty Saddle Italian horses (11 geldings and 9 females, 9 ± 1 years old, body weight of 425 ± 35 kg) were divided into two equal groups according to the intensity of training programs they were subjected: group A was subjected to an intense training program, group B was subjected to a moderate training program. At the end of the training period, horses were subjected to a simulated exercise event (show jumping course of 400 m length with 12 obstacles). From horses, blood samples were collected at rest conditions (T) and after 12 and 24 hour from the end of exercise (T and T); the concentration of serum amyloid A (SAA), haptoglobin, albumin, total proteins, iron, and fibrinogen was assessed. The circulating levels of SAA, fibrinogen, and iron were influenced by simulated exercise event (P < .01), starting from 12 hour after the end of exercise, suggesting the onset of an acute phase-like response, and it would seem that training program intensity the horses underwent also affected the degree of response, although only SAA values were significantly different between groups (P < .001). The findings obtained suggest that jumping exercise induces an acute phase response; however, further studies are advocated to better evaluate mechanisms by which exercise activates this response in the athletic horse.
生理和血液化学变化与运动有关已在马属动物中进行了广泛的研究。已知应激会升高急性期蛋白（APPs）的循环水平。本研究评估了不同训练计划训练的马在运动事件后 APP 水平是否发生变化。20 匹意大利鞍马（11 匹公马和 9 匹母马，9 ± 1 岁，体重 425 ± 35kg）根据所接受的训练计划的强度分为两组：A 组接受高强度训练计划，B 组接受中等强度训练计划。在训练期结束时，马进行了模拟运动事件（400m 长的障碍赛有 12 个障碍）。在休息条件下（T）和运动结束后 12 和 24 小时（T 和 T）从马身上采集血液样本；评估血清淀粉样蛋白 A（SAA）、触珠蛋白、白蛋白、总蛋白、铁和纤维蛋白原的浓度。SAA、纤维蛋白原和铁的循环水平受模拟运动事件的影响（P <.01），从运动结束后 12 小时开始，表明发生了急性期样反应，而且似乎马所经历的训练计划强度也影响了反应程度，尽管仅 SAA 值在组间有显著差异（P <.001）。研究结果表明，跳跃运动可引起急性期反应；然而，建议进行进一步的研究以更好地评估运动激活运动马这种反应的机制。
