Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, No.7, Zhongshan S. Rd., Zhongzheng Dist., Taipei City, 100, Taiwan.
Department of Anesthesiology, National Taiwan University Hospital and National Taiwan University College of Medicine, No.7, Zhongshan S. Rd., Zhongzheng Dist., Taipei City, 100, Taiwan; Department of Anesthesiology, National Taiwan University Hospital and National Taiwan University College of Medicine Hsin-Chu-Lin Branch, NO.25, Lane 442, Sec.1, Jingguo Rd., Hsinchu City, 300, Taiwan.
J Formos Med Assoc. 2020 Sep;119(9):1396-1404. doi: 10.1016/j.jfma.2020.03.021. Epub 2020 Apr 14.
Uniportal thoracoscopic segmentectomy under intubated general anesthesia with one-lung ventilation has recently been introduced for the management of lung cancer patients with small tumors or compromised cardiopulmonary function. However, uniportal thoracoscopic segmentectomy without endotracheal intubation had rarely been performed. Therefore, in this study, we aimed to evaluate the feasibility and safety of this novel technique.
From January 2014 to November 2018, 32 lung cancer patients were treated using nonintubated uniportal thoracoscopic segmentectomy under a combination of target-controlled infusion of propofol, nasal high-flow oxygen therapy, intrathoracic intercostal nerve blockade, and vagal nerve blockade. Sixty-two other lung cancer patients who underwent initial planning nonintubated multiportal thoracoscopic segmentectomy during the same period were included as the control group.
Preoperative dye localization was required in 18 (56.3%) patients of uniportal group. No patients required conversion to tracheal intubation or thoracotomy. Two patients were converted from the one-port to the two-port approach due to severe adhesions in the pleural cavity. The mean durations of anesthetic induction and surgery were 12.7 min and 101.1 min, respectively. Postoperative complications were noted in two patients (2/32, 6.3%) of uniportal group: one had subcutaneous emphysema and the other had prolonged air leaks over 3 days. The median durations of postoperative chest drainage and hospital stay were 1 and 3 days in uniportal group, respectively.
Nonintubated uniportal thoracoscopic segmentectomy is technically feasible and safe for selected patients. It can be an attractive alternative to intubated thoracoscopic segmentectomy for patients with early lung cancer.
经气管插管全身麻醉下单操作孔电视胸腔镜肺段切除术最近被引入用于治疗患有小肿瘤或心肺功能受损的肺癌患者。然而,无气管插管的单操作孔电视胸腔镜肺段切除术很少被实施。因此,在本研究中,我们旨在评估该新技术的可行性和安全性。
从 2014 年 1 月至 2018 年 11 月,32 例肺癌患者在靶控输注异丙酚、鼻高流量吸氧、肋间神经阻滞和迷走神经阻滞联合下接受非插管单操作孔电视胸腔镜肺段切除术治疗。同期,62 例肺癌患者接受初始计划非插管多孔电视胸腔镜肺段切除术作为对照组。
单操作孔组中有 18 例(56.3%)患者需要术前染料定位。无患者需要转为气管插管或开胸。由于胸腔内严重粘连,2 例患者从单孔改为双孔入路。麻醉诱导和手术的平均时间分别为 12.7 分钟和 101.1 分钟。单操作孔组有 2 例(2/32,6.3%)患者出现术后并发症:1 例皮下气肿,1 例持续漏气超过 3 天。单操作孔组患者术后胸腔引流和住院时间的中位数分别为 1 天和 3 天。
对于选择的患者,非插管单操作孔电视胸腔镜肺段切除术在技术上是可行和安全的。对于早期肺癌患者,它可能是气管插管电视胸腔镜肺段切除术的一种有吸引力的替代方法。