Tsai Tung-Ming, Lin Mong-Wei, Hsu Hsao-Hsun, Chen Jin-Shing
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
J Vis Surg. 2017 Nov 6;3:155. doi: 10.21037/jovs.2017.08.21. eCollection 2017.
Minimal invasive surgery is current choice of treatment for lung cancer. Combined nonintubated anesthesia with uniportal thoracoscopic surgery is not well understood. Here, we report the experience of nonintubated uniportal thoracoscopic surgery in the treatment of primary non-small cell lung cancer (NSCLC).
From January 2014 to December 2015, we retrospectively reviewed 131 consecutive patients with primary NSCLC who underwent nonintubated uniportal thoracoscopic wedge resection and mediastinal lymph node dissection at a single medical center.
Of the 131 patients, 110 (84%) received preoperative computed tomography-guided dye localization. Most of them were diagnosed with early stage invasive adenocarcinoma (N=112, 85.5%; pathological stage IA: 84.7%, N=111), and the mean size of the nodule was small (diameter: 0.85±0.40 cm). All section margins were free of malignancy. In total, 7 of the 131 patients (5.3%) had their treatment converted from uniportal to multi-portal video-assisted thoracoscopic surgery (VATS), and 1 (0.8%) had his treatment converted to endotracheal intubation with general anesthesia. The mean operation time was 91.1±32.6 minutes, and the postoperative complications included pneumonia (0.8%), prolonged air leaks (0.8%), and subcutaneous emphysema (1.5%).
Overall, nonintubated uniportal VATS is a feasible, effective and safe procedure for the treatment of early primary lung cancer.
微创手术是目前肺癌的治疗选择。非插管麻醉联合单孔胸腔镜手术的情况尚不完全清楚。在此,我们报告非插管单孔胸腔镜手术治疗原发性非小细胞肺癌(NSCLC)的经验。
2014年1月至2015年12月,我们回顾性分析了在单一医疗中心连续接受非插管单孔胸腔镜楔形切除术和纵隔淋巴结清扫术的131例原发性NSCLC患者。
131例患者中,110例(84%)接受了术前计算机断层扫描引导下的染料定位。大多数患者被诊断为早期浸润性腺癌(N = 112,85.5%;病理分期IA:84.7%,N = 111),结节平均大小较小(直径:0.85±0.40 cm)。所有切缘均无恶性肿瘤。131例患者中,共有7例(5.3%)的治疗方式从单孔转换为多孔电视辅助胸腔镜手术(VATS),1例(0.8%)的治疗方式转换为气管插管全身麻醉。平均手术时间为91.1±32.6分钟,术后并发症包括肺炎(0.8%)、持续性漏气(0.8%)和皮下气肿(1.5%)。
总体而言,非插管单孔VATS是治疗早期原发性肺癌的一种可行、有效且安全的手术方法。