Voynick I M, Makuch R W
Yale University School of Medicine, Department of Epidemiology and Public Health, New Haven, Connecticut 06510.
J Med Syst. 1988 Oct;12(5):295-304. doi: 10.1007/BF00996580.
A computerized system for the management of a clinical research database has been developed with several attractive features. This relational database management system allows for screen-driven data entry, data checking, system security, and report generation in a timely manner. In addition, the system is cost-effective in a number of ways: (1) development time is considerably reduced due to the inherent programming features of the software, (2) once developed the system can be maintained by nontechnical personnel thereby reducing personnel costs, (3) the system can be developed and maintained on a microcomputer system, and (4) the commercial software used in our system is periodically updated thereby assuring the user of state-of-the-art technology. Beyond the initial expenditures for hardware and software, no additional system costs are incurred. While this system, currently adopted by the Yale Comprehensive Cancer Center, represents an effective approach to handling the data-management needs of a large, single-institution cancer research center, the design and programming methodology can be readily adapted to other research settings.
已开发出一个用于临床研究数据库管理的计算机化系统，该系统具有若干吸引人的特性。这个关系数据库管理系统允许通过屏幕驱动进行数据录入、数据检查、系统安全设置以及及时生成报告。此外，该系统在多个方面具有成本效益：（1）由于软件固有的编程特性，开发时间大幅减少；（2）一旦开发完成，非技术人员即可维护该系统，从而降低人员成本；（3）该系统可在微型计算机系统上进行开发和维护；（4）我们系统中使用的商业软件会定期更新，从而向用户保证采用了最先进的技术。除了硬件和软件的初始支出外，不会产生额外的系统成本。虽然耶鲁综合癌症中心目前采用的这个系统代表了一种处理大型单机构癌症研究中心数据管理需求的有效方法，但该设计和编程方法很容易适用于其他研究环境。
