From the Keck School of Medicine, University of Southern California, Los Angeles, CA.
Female Pelvic Med Reconstr Surg. 2021 May 1;27(5):328-333. doi: 10.1097/SPV.0000000000000840.
The aim of this study was to investigate whether receiving a clinical diagnosis of interstitial cystitis (IC) or bladder pain syndrome (BPS) improves patients' symptoms, health-related quality of life (HRQOL), or ability to cope with their symptoms.
In this cross-sectional study, participants with self-reported IC/BPS completed an online questionnaire recalling their perceived change in symptoms after diagnosis and treatment. The questionnaire included demographic information, overall HRQOL measured on a visual analog scale (VAS), O'Leary-Sant Interstitial Cystitis Problem Index, the Urinary Impact Questionnaire, and questions regarding patient beliefs about diagnosis. HRQOL and symptom impact scales were compared before and after diagnosis and treatment. Demographic data, symptom data, and beliefs were examined for correlation with improvement in quality of life after diagnosis.
A total of 1052 participants initiated the survey and were included in the analysis; most of them identified as female, non-Hispanic, and white (90%). Before symptom onset, median VAS HRQOL score was 87 (interquartile range [IQR], 77-95). Median scores nadired at 34 (IQR, 20-59) after symptom onset before diagnosis, but improved to 61 after diagnosis and treatment (IQR, 38-74; all P < 0.001). Scores remained stable after diagnosis and initiation of treatment with a median score of 65 at the time of survey (IQR, 37-80; P > 0.05). Age, insurance type, and improvement in scores on the symptom impact scale predicted improvement in HRQOL after diagnosis and treatment in the multivariable model.
Participants reported improvements on global and symptom-specific quality of life measures after diagnosis and treatment for IC/BPS.
本研究旨在探讨临床诊断间质性膀胱炎（IC）或膀胱疼痛综合征（BPS）是否能改善患者的症状、健康相关生活质量（HRQOL）或应对症状的能力。
在这项横断面研究中，自我报告患有 IC/BPS 的参与者完成了一份在线问卷，回忆他们在诊断和治疗后症状的变化感知。问卷包括人口统计学信息、视觉模拟量表（VAS）上的整体 HRQOL、O'Leary-Sant 间质性膀胱炎问题指数、尿影响问卷以及关于患者对诊断的看法的问题。在诊断和治疗前后比较了 HRQOL 和症状影响量表。检查人口统计学数据、症状数据和信念与诊断后生活质量改善的相关性。
共有 1052 名参与者启动了调查并被纳入分析；他们大多为女性、非西班牙裔和白人（90%）。在症状出现前，VAS HRQOL 评分中位数为 87（四分位距 [IQR]，77-95）。在诊断前症状出现后，中位数评分降至 34（IQR，20-59），但在诊断和治疗后改善至 61（IQR，38-74；均 P<0.001）。在诊断和开始治疗后，评分保持稳定，在调查时的中位数评分为 65（IQR，37-80；P>0.05）。年龄、保险类型和症状影响量表评分的改善在多变量模型中预测了诊断和治疗后 HRQOL 的改善。
参与者报告在 IC/BPS 的诊断和治疗后，全球和症状特异性生活质量测量均有所改善。
