从皮脂腺导管发育而来的穹隆部角化囊肿：病例报告并免疫组化分析。
Keratinous Cyst of the Caruncle Developing From a Sebaceous Gland Duct: Case Report With Immunohistochemical Analysis.
机构信息
Department of Ophthalmology, New York University Langone Medical Center, New York, New York.
Department of Pathology, New York University Langone Medical Center, New York, New York, U.S.A.
出版信息
Ophthalmic Plast Reconstr Surg. 2020 Nov/Dec;36(6):e139-e140. doi: 10.1097/IOP.0000000000001656.
An enlarging white caruncular cyst in a 24-year-old woman proved to be a keratinous cyst lined by keratinizing squamous epithelium that lacked a keratohyalin granular layer (trichilemmal keratinization). The cyst most likely originated from a sebaceous gland duct. A panel of immunohistochemical stains was employed that compared and contrasted the cyst lining with the overlying caruncular conjunctival epithelium and further eliminated the likelihood of a conjunctival cyst. The most useful confirmatory stains were the positive trichilemmal marker calretinin, the positive sebaceous ductal marker cytokeratin 17 (suprabasal epithelium), and the negative conjunctival markers cytokeratins 7 and 19. Only one previous report of a very rare similar caruncular cyst is recorded in the literature without an extensive immunohistochemical analysis.
一名 24 岁女性的增大的白色肉阜状囊肿被证实为角化囊肿，由角化的鳞状上皮构成，缺乏角蛋白透明颗粒层（毛母质角化）。该囊肿很可能起源于皮脂腺导管。进行了一组免疫组织化学染色，将囊壁与上方的肉阜状结膜上皮进行比较和对比，并进一步排除了结膜囊肿的可能性。最有用的确认性染色是阳性的毛母质标志物钙视网膜蛋白、阳性的皮脂腺导管标志物细胞角蛋白 17（基层以上上皮）和阴性的结膜标志物细胞角蛋白 7 和 19。文献中仅记录了一例非常罕见的类似肉阜状囊肿的先前报道，但未进行广泛的免疫组织化学分析。
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