Holmes Emily A, O'Connor Rory C, Perry V Hugh, Tracey Irene, Wessely Simon, Arseneault Louise, Ballard Clive, Christensen Helen, Cohen Silver Roxane, Everall Ian, Ford Tamsin, John Ann, Kabir Thomas, King Kate, Madan Ira, Michie Susan, Przybylski Andrew K, Shafran Roz, Sweeney Angela, Worthman Carol M, Yardley Lucy, Cowan Katherine, Cope Claire, Hotopf Matthew, Bullmore Ed
Department of Psychology, Uppsala University, Uppsala, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Suicidal Behaviour Research Laboratory, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Lancet Psychiatry. 2020 Jun;7(6):547-560. doi: 10.1016/S2215-0366(20)30168-1. Epub 2020 Apr 15.
The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health. We explore the psychological, social, and neuroscientific effects of COVID-19 and set out the immediate priorities and longer-term strategies for mental health science research. These priorities were informed by surveys of the public and an expert panel convened by the UK Academy of Medical Sciences and the mental health research charity, MQ: Transforming Mental Health, in the first weeks of the pandemic in the UK in March, 2020. We urge UK research funding agencies to work with researchers, people with lived experience, and others to establish a high level coordination group to ensure that these research priorities are addressed, and to allow new ones to be identified over time. The need to maintain high-quality research standards is imperative. International collaboration and a global perspective will be beneficial. An immediate priority is collecting high-quality data on the mental health effects of the COVID-19 pandemic across the whole population and vulnerable groups, and on brain function, cognition, and mental health of patients with COVID-19. There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19. Discovery, evaluation, and refinement of mechanistically driven interventions to address the psychological, social, and neuroscientific aspects of the pandemic are required. Rising to this challenge will require integration across disciplines and sectors, and should be done together with people with lived experience. New funding will be required to meet these priorities, and it can be efficiently leveraged by the UK's world-leading infrastructure. This Position Paper provides a strategy that may be both adapted for, and integrated with, research efforts in other countries.
2019年冠状病毒病(COVID-19)大流行正在对社会的各个方面产生深远影响,包括心理健康和身体健康。我们探讨了COVID-19的心理、社会和神经科学影响,并阐述了心理健康科学研究的近期优先事项和长期战略。这些优先事项是根据对公众的调查以及2020年3月英国大流行最初几周由英国医学科学院和心理健康研究慈善机构MQ:改善心理健康召集的一个专家小组的意见确定的。我们敦促英国研究资助机构与研究人员、有实际生活经历的人以及其他各方合作,成立一个高级协调小组,以确保这些研究优先事项得到落实,并随着时间的推移确定新的优先事项。维持高质量研究标准的必要性至关重要。国际合作和全球视野将大有裨益。当务之急是收集关于COVID-19大流行对全体人口和弱势群体心理健康影响以及对COVID-19患者脑功能、认知和心理健康影响的高质量数据。迫切需要开展研究,以解决在大流行情况下如何减轻弱势群体的心理健康后果,以及反复接触媒体和围绕COVID-19的健康信息所产生的影响。需要发现、评估和完善以机制为驱动的干预措施,以应对大流行的心理、社会和神经科学方面的问题。应对这一挑战需要跨学科和跨部门的整合,并且应该与有实际生活经历的人共同进行。需要新的资金来满足这些优先事项,英国领先世界的基础设施可以有效地利用这些资金。本立场文件提供了一种既可以适用于其他国家的研究工作,又可以与之整合的战略。