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研究方案:监禁释放后一年降低自杀风险的随机对照试验(SPIRIT 试验)。

Study Protocol: A randomized controlled trial of suicide risk reduction in the year following jail release (the SPIRIT Trial).

机构信息

Michigan State University College of Human Medicine, 200 East 1(st) St Room 366, Flint, MI 48503, United States of America.

Brown University Warren Alpert Medical School, 700 Butler Drive, Providence, RI 02906, United States of America.

出版信息

Contemp Clin Trials. 2020 Jul;94:106003. doi: 10.1016/j.cct.2020.106003. Epub 2020 Apr 15.

Abstract

PURPOSE

This article describes the protocol for a randomized effectiveness and cost-effectiveness trial of Stanley and Brown's Safety Planning Intervention (SPI) during pretrial jail detention to reduce post-release suicide events (suicide attempts, suicide behaviors, and suicide-related hospitalizations).

BACKGROUND

With 10 million admissions per year and short stays (often days), U.S. jails touch many individuals at risk for suicide, providing an important opportunity for suicide prevention that is currently being missed. This study (N = 800) is the first randomized evaluation of an intervention to reduce suicide risk in the vulnerable year after jail release. Given that roughly 10% of all suicides in the U.S. with known circumstances occur in the context of a criminal legal stressor, reducing suicide risk in the year after arrest and jail detention could have a noticeable impact on national suicide rates.

DESIGN

Pretrial jail detainees at risk for suicide were randomized to SPI during jail detention plus post-release phone follow-up or to enhanced Standard Care. Outcomes assessed through 12 months post-release include suicide events, suicide attempts, weeks of active suicide ideation, severity of suicide ideation, time to first event, psychiatric symptoms, functioning, and cost-effectiveness. Methods accommodate short jail stays and maximize trial safety and follow-up in a large sample with severe suicide risk, access to lethal means including substances and firearms, high rates of psychiatric illness, and unstable circumstances.

CONCLUSION

Adequate funding was important to create the infrastructure needed to run this large trial cleanly. We encourage funders to provide adequate resources to ensure clean, well-run trials.

摘要

目的

本文介绍了斯坦利和布朗安全计划干预(SPI)在审前拘留期间进行的一项随机有效性和成本效益试验的方案,以减少释放后自杀事件(自杀企图、自杀行为和与自杀相关的住院治疗)。

背景

美国每年有 1000 万人入狱,拘留时间短(通常只有几天),接触到许多有自杀风险的人,为预防自杀提供了一个重要的机会,但目前这一机会还未被充分利用。这项研究(N=800)是首个评估干预措施以降低入狱后一年内自杀风险的随机评估。鉴于美国大约 10%的已知情况下发生的自杀事件与刑事法律应激源有关,降低逮捕和入狱后一年内的自杀风险可能会对全国自杀率产生显著影响。

设计

有自杀风险的审前拘留人员随机分配到 SPI 组(在拘留期间加用 SPI 并在释放后进行电话随访)或增强型标准护理组。通过释放后 12 个月评估的结果包括自杀事件、自杀企图、有自杀意念的活跃周数、自杀意念严重程度、首次事件时间、精神症状、功能和成本效益。方法适应短期拘留,并在有严重自杀风险、有获得致命手段(包括药物和枪支)、高精神疾病发病率和不稳定环境的大样本中最大限度地提高试验安全性和随访率。

结论

充足的资金对于建立运行这个大型试验所需的基础设施非常重要。我们鼓励资助者提供充足的资源,以确保试验的清洁和良好运行。

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