Lantos P R
Target Group Inc., Philadelphia, PA 19118.
J Biomater Appl. 1988 Jan;2(3):358-71. doi: 10.1177/088532828700200305.
Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile. By performing capably and reliably in these applications, plastics have found a major outlet, one that offers good opportunities for the present materials as well as for future developments. Numerous challenges remain. The present materials perform, though barely adequately, and superior performance over longer periods of time is an important goal. While off-the-shelf plastics have been used in most medical applications, it is likely that development work will focus on the needs of specific important medical applications. In addition to the usual need for ever decreasing costs and prices, there is the opportunity for materials that possess improved blood compatibility, radiation resistance, and/or in vivo compatibility for improved degradable sutures, coatings for pacemakers, phthalate-free plastics, bags with improved gas impermeability and disposables with controlled degradability.
