Tetz M R, O'Morchoe D J, Gwin T D, Wilbrandt T H, Solomon K D, Hansen S O, Apple D J
Department of Ophthalmology, University of Utah Health Sciences Center, Salt Lake City.
J Cataract Refract Surg. 1988 Nov;14(6):614-23. doi: 10.1016/s0886-3350(88)80028-2.
In a prospective randomized study, 25 New Zealand white rabbit eyes were implanted with four intraocular lens (IOL) designs. These included a one-piece modified J-loop IOL, a three-piece modified J-loop IOL, a rigid disc IOL, and an experimental compressible disc (CD) IOL. The CD IOL revealed the lowest mean posterior capsular opacification (PCO) of all IOLs tested (P less than .01). With all lenses tested, a positive correlation between PCO and decentration was found (R = 0.55, P less than .05). These results suggest that because of its design features (i.e., one-piece construction, biconvex optic, posterior angulation of the fixation element), the CD lens produces a mechanical barrier against lens epithelial cell migration and reduces the incidence of PCO.
在一项前瞻性随机研究中，对25只新西兰白兔眼植入了四种人工晶状体（IOL）设计。这些包括一片式改良J袢人工晶状体、三片式改良J袢人工晶状体、刚性盘状人工晶状体和一种实验性可压缩盘状（CD）人工晶状体。在所有测试的人工晶状体中，CD人工晶状体显示出最低的平均后囊膜混浊（PCO）（P<0.01）。在所有测试的晶状体中，发现PCO与偏心之间存在正相关（R = 0.55，P<0.05）。这些结果表明，由于其设计特点（即一体式结构、双凸光学部、固定元件的后倾角），CD晶状体对晶状体上皮细胞迁移产生机械屏障并降低了PCO的发生率。
