肠道病毒 D68 的受体结合分析

Receptor-Binding Assays of Enterovirus D68.

机构信息

Center for Postgraduate Education and Training, National Center for Child Health and Development, Tokyo, Japan.

Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

出版信息

Methods Mol Biol. 2020;2132:629-639. doi: 10.1007/978-1-0716-0430-4_54.

DOI:10.1007/978-1-0716-0430-4_54

PMID:32306362

Abstract

Human enterovirus D68 (EV-D68) is a causative agent for acute respiratory infections and potentially central nervous system illnesses with increasing epidemiological significance. Recent studies have highlighted the role of sialic acids as a functional receptor for EV-D68 in vitro. However, further investigations are required to reveal its significance in actual infections in human.

摘要

人类肠道病毒 D68（EV-D68）是一种引起急性呼吸道感染和潜在中枢神经系统疾病的病原体，其流行病学意义日益增加。最近的研究强调了唾液酸作为 EV-D68 在体外的功能性受体的作用。然而，需要进一步的研究来揭示其在人类实际感染中的意义。