Ma K, Chen T, Han M F, Guo W, Ning Q
Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhonghua Gan Zang Bing Za Zhi. 2020 Mar 20;28(3):222-228. doi: 10.3760/cma.j.cn50113-20200220-00056.
Coronavirus disease 2019 (COVID-19) outbreak in Wuhan city, Hubei province in December 2019 and the epidemic so rapidly happened within the whole country and abroad, raising serious problems and urgent concerns, such as: how to control most effectively human-to-human transmission? When does infection rate rise to its peak? What will eventually be the number of infected patients? How to make early diagnosis? What effective antiviral drugs are available? How to use the existing drugs to achieve the best effect? Can available drugs effectively improve the survival rate of critical patients? In view of the above questions, this article now puts forwards the corresponding suggestions and considerations from the perspective of clinical infectious diseases physician.
2019年12月,湖北省武汉市爆发了2019冠状病毒病(COVID-19),疫情在国内外迅速蔓延,引发了严重问题和紧迫关切,例如:如何最有效地控制人际传播?感染率何时升至峰值?最终感染患者数量会是多少?如何进行早期诊断?有哪些有效的抗病毒药物?如何使用现有药物达到最佳效果?现有药物能否有效提高重症患者的生存率?鉴于上述问题,本文现从临床传染病医生的角度提出相应的建议和思考。