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吸食麦角酸二乙酰胺(“浴盐”)后的精神病学特征。

The Psychiatric Characteristics of People on a Mephedrone ("bath salts") Binge.

机构信息

Department of Pharmacodynamics, Centre for Preclinical, Research and Technology (CePT), Medical University of Warsaw, Warsaw, Poland.

Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland.

出版信息

Subst Use Misuse. 2020;55(10):1610-1617. doi: 10.1080/10826084.2020.1753775. Epub 2020 Apr 20.

Abstract

: Despite solutions presented by the European Union and national regulations introduced by many countries, the problem of mephedrone (4-MMC) is growing. : The aim of this study was to investigate the effect of regular mephedrone intake with other psychoactive substances on the clinical picture of patients, including self-harms and suicide attempts. : The study involved a group of 601 patients addicted to mephedrone who were admitted to a psychiatric hospital between 2010 and 2018 due to regular mephedrone intake. : There was a statistically significant relationship between sleep disorders and mephedrone combined with alcohol ( < .05) or cannabinols ( < .05). However, the highest number of statistically significant correlations was reported when mephedrone was combined with opioids. There was a growing year-on-year percentage of people who attempted suicide because of regular mephedrone intake ( < .001). The more psychoactive substances were combined with mephedrone, the greater the risk of attempted suicide ( < .01). 20% of the examined group were hospitalized several times. Among those hospitalized several times, significantly more people took more than one additional psychoactive substance ( < .01). : The more psychoactive substances combined with mephedrone, the more clinical symptoms are associated with it.

摘要

尽管欧盟和许多国家都提出了一些解决方案,但 4-甲基甲卡西酮(mephedrone,4-MMC)的问题仍在不断加剧。本研究旨在调查经常摄入 4-MMC 与其他精神活性物质共同作用对患者临床症状的影响,包括自伤和自杀企图。该研究涉及 2010 年至 2018 年间因经常摄入 4-MMC 而被收治于一家精神病院的 601 名 4-MMC 成瘾患者。睡眠障碍与 4-MMC 联合酒精( < .05)或大麻素( < .05)之间存在统计学显著关系。然而,当 4-MMC 与阿片类药物联合使用时,报告的统计学显著相关性数量最高。由于经常摄入 4-MMC 而自杀企图的人数逐年增加( < .001)。与 4-MMC 联合使用的精神活性物质越多,自杀企图的风险就越大( < .01)。被检查人群中有 20%的人多次住院。在多次住院的人群中,明显有更多的人同时使用了一种以上的其他精神活性物质( < .01)。与 4-MMC 联合使用的精神活性物质越多,与之相关的临床症状就越多。

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