Suppr超能文献

一项关于使用速效胰岛素Aspart 的 1 型或 2 型糖尿病患者的医生经验和治疗满意度的调查。

A survey of physician experience and treatment satisfaction using fast-acting insulin aspart in people with type 1 or type 2 diabetes.

机构信息

Global Primary Intelligence, IQVIA , Rotkreuz, Switzerland.

Primary Intelligence, IQVIA , Gurgaon, India.

出版信息

Postgrad Med. 2020 May;132(4):320-327. doi: 10.1080/00325481.2020.1750181. Epub 2020 Apr 20.

Abstract

AIMS

This survey aimed to explore real-world physician experiences and treatment satisfaction with fast-acting insulin aspart (faster aspart) in clinical practice across Europe and Canada.

MATERIALS AND METHODS

An online web-based survey was used for physicians treating people with type 1 or type 2 diabetes. General practitioners and specialists, with experience using faster aspart, were interviewed.

RESULTS

A total of 191 physicians participated in the survey. Most of their patients (68% of those with T1D and 63% of those with T2D) were previously treated with another mealtime insulin before switching to faster aspart. At the time of initiating faster aspart, nearly half of patients had an HbA level between 7.5% (59 mmol/mol) and 8.5% (69 mmol/mol). The main prescription drivers for faster aspart, versus other mealtime insulins, were faster onset of action, improved postprandial glucose (PPG) control, and dosing flexibility. Most physicians were more satisfied with faster aspart than other mealtime insulins regarding at-meal (66%) and post-meal (71%) dosing flexibility, improved PPG levels (66%), and onset of action (61%). Main reasons for not prescribing faster aspart included a good response to current treatment (76%) or patient reluctance to switch (57%). Overall, 12% of patients discontinued faster aspart, for reasons including concerns of hypoglycemia (17%), poor adherence (17%), and level of patient co-pay (17%). More than half of physicians had fewer concerns regarding postprandial hyperglycemia, and were more confident in their patients reaching their HbA target with faster aspart than with other mealtime insulins.

LIMITATIONS

The findings of this survey are based heavily on physicians' experiences, and could therefore be subject to recall bias.

CONCLUSIONS

Reported physician and patient experiences of using faster aspart have been positive, and better PPG control and increased dosing flexibility are expected to improve glycemic management.

摘要

目的

本研究旨在探索欧洲和加拿大的临床医生在使用速效门冬胰岛素(faster aspart)治疗 1 型或 2 型糖尿病患者时的真实体验和治疗满意度。

材料和方法

本研究采用在线网络调查的方式,对使用过 faster aspart 的 1 型或 2 型糖尿病患者的医生进行调查。

结果

共有 191 名医生参与了本研究。他们的大多数患者(68%的 1 型糖尿病患者和 63%的 2 型糖尿病患者)在改用 faster aspart 之前曾使用过另一种餐时胰岛素。在开始使用 faster aspart 时,近一半的患者的 HbA1c 水平在 7.5%(59mmol/mol)至 8.5%(69mmol/mol)之间。与其他餐时胰岛素相比,医生选择 faster aspart 的主要原因是起效更快、改善餐后血糖(PPG)控制和剂量灵活性。大多数医生认为 faster aspart 比其他餐时胰岛素在餐时(66%)和餐后(71%)剂量灵活性、改善 PPG 水平(66%)和起效时间(61%)方面更具优势。不选择 faster aspart 的主要原因包括对当前治疗的反应良好(76%)或患者不愿换药(57%)。总体而言,有 12%的患者因担心低血糖(17%)、依从性差(17%)和患者自付费用水平(17%)等原因停用了 faster aspart。超过一半的医生对餐后高血糖的担忧较少,并且对使用 faster aspart 使患者达到 HbA1c 目标的信心比对其他餐时胰岛素的信心更强。

局限性

本研究结果主要基于医生的经验,因此可能存在回忆偏倚。

结论

报告的医生和患者使用 faster aspart 的经验是积极的,更好的 PPG 控制和增加的剂量灵活性有望改善血糖管理。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验