Poltavskaya T S, Bazhenov V A, Volojanin A V
Central City Clinical Hospital #6, Yekaterinburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(3. Vyp. 2):49-53. doi: 10.17116/jnevro202012003249.
To evaluate the efficacy of including cytoflavin in rehabilitation measures in the early recovery period of patients with ischemic stroke.
Results of rehabilitation measures of 100 patients (50 women and 50 men, aged 18 to 85 years) in the early recovery period of ischemic stroke were analyzed. Psychological testing included NIHSS, MMSE, Rankin scale, Rivermead mobility index, exercise tolerance test. Depending on the rehabilitation scheme, patients were divided into the main group (n=50), who received a verticalization course and cytoflavin (intravenously, drip 20.0 ml in 250.0 ml 5% glucose for 14 days). The control group (n=50) included patients who received standard treatment.
Inclusion of cytoflavin in the rehabilitation scheme for patients with ischemic stroke increased the effectiveness of treatment, which was manifested by a decrease in the severity of neurological disorders assessed with NIHSS by 17.6% in the main group versus 10.8% in the control group (p<0.05) and recovery of cognitive functions assessed with MMSE by 5.8% versus 1.6%, respectively (p<0.05). In addition, there was a positive dynamics in the restoration of blood pressure (by 37.1% in the main group versus 30.6% in the control group (p<0.05)).
评估在缺血性脑卒中患者早期恢复阶段的康复措施中加入细胞色素C的疗效。
分析100例（50名女性和50名男性，年龄18至85岁）缺血性脑卒中早期恢复阶段患者的康复措施结果。心理测试包括美国国立卫生研究院卒中量表（NIHSS）、简易精神状态检查表（MMSE）、Rankin量表、Rivermead运动指数、运动耐量测试。根据康复方案，患者被分为主要组（n = 50），接受直立训练疗程和细胞色素C（静脉滴注，在250.0 ml 5%葡萄糖中滴注20.0 ml，共14天）。对照组（n = 50）包括接受标准治疗的患者。
在缺血性脑卒中患者的康复方案中加入细胞色素C可提高治疗效果，主要表现为主要组用NIHSS评估的神经功能障碍严重程度降低了17.6%，而对照组降低了10.8%（p<0.05）；用MMSE评估的认知功能恢复率分别为5.8%和1.6%（p<0.05）。此外，血压恢复方面也呈现积极变化（主要组为37.1%，对照组为30.6%，p<0.05）。
