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卵巢间质增生:绝经后高雄激素血症的罕见病因。

Ovarian Stromal Hyperplasia: A Rare Cause of Postmenopausal Hyperandrogenism.

作者信息

Lozoya Araque Teresa, Monfort Ortiz Isauro Rogelio, Martín González José Enrique, Jiménez García Alenda, Navarro Hidalgo Inmaculada, Andrade Gamarra Verónica, Parrell Soler Cecilia, Gil Raga Fernando

机构信息

Department of Obstetrics and Gynecology, Manises Hospital, Valencia, Spain.

Department of Obstetrics and Gynecology, La Fe University Hospital, Valencia, Spain.

出版信息

J Menopausal Med. 2020 Apr;26(1):39-43. doi: 10.6118/jmm.19012.

Abstract

Ovarian hyperthecosis and ovarian stromal hyperplasia (OSH) are two uncommon non-neoplastic causes of ovarian hyperandrogenism, whose etiology is still unknown. These conditions are characterized by obesity, hyperinsulinemia, acanthosis nigricans, and even virilization, mainly in postmenopausal women. Here we have reported the case of a 67-year-old patient with a diagnosis of OSH, which was resolved after bilateral laparoscopic oophorectomy. In this case report, we have discussed two different conditions posing a diagnostic challenge and requiring a high index of suspicion.

摘要

卵巢泡膜细胞增生症和卵巢间质增生(OSH)是卵巢雄激素过多症的两种罕见的非肿瘤性病因,其病因仍不明。这些病症的特征为肥胖、高胰岛素血症、黑棘皮症,甚至男性化,主要见于绝经后女性。在此,我们报告了一例67岁诊断为OSH的患者,该患者在双侧腹腔镜卵巢切除术后病情得到缓解。在本病例报告中,我们讨论了两种造成诊断困难且需要高度怀疑指数的不同病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e43/7160587/3c1be2704a3e/jmm-26-39-g001.jpg

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