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无症状绝经后女性盆腔器官的超声参数及其与年龄的相关性变化:一项基于社区的研究。

Ultrasound parameters of pelvic organs and their age-related changes in a cohort of asymptomatic postmenopausal women: A community-based study.

机构信息

Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.

University Obstetrics and Gynaecology Unit, North Colombo Teaching Hospital, Ragama, Sri Lanka.

出版信息

Post Reprod Health. 2020 Sep;26(3):147-154. doi: 10.1177/2053369120915145. Epub 2020 Apr 19.

Abstract

OBJECTIVE

To describe the ultrasound parameters of pelvic organs and their age-related changes in a cohort of asymptomatic postmenopausal women and to describe the prevalence of ultrasound-detected pathologies in a Sri Lankan population.

STUDY DESIGN

A large community-based longitudinal study using a randomly selected sample of postmenopausal women who have never used hormone replacement therapy.

MAIN OUTCOME MEASURES

Uterine, endometrial and ovarian measurements at pelvic ultrasonography as described by the International Endometrial Tumor Analysis and the International Ovarian Tumor Analysis groups.

RESULTS

A total of 815 postmenopausal women were approached and all volunteered to participate. This included women between the ages of 45 and 74 years with a median (interquartile range (IQR)) of 62.0 (10.0) years. The median (IQR) uterine volume was 18.1 (17) ml, while the median (IQR) of right and left ovarian volumes were 17.3 (22.9) ml and 18.2 (21.5) ml. Both uterine and ovarian volumes showed an age-related decline (p < 0.01). Furthermore, the ovarian volumes demonstrated an increase in size with a higher body mass index (p < 0.03 for left and p < 0.01 for right, respectively). Median (IQR) endometrial thickness among the population was 3.0 (1.0) mm and there was no age-related change observed. Sixty-one women had an ultrasound-detected gynaecological pathology with a prevalence of 7.5% (95% confidence interval (CI) 5.6-9.5).

CONCLUSIONS

This study aimed at describing ultrasound parameters of pelvic organs among postmenopausal women of Sri Lanka was able to provide the reference values for uterine and ovarian volume among asymptomatic postmenopausal women. Both uterine and ovarian volumes demonstrated an age-related decline, whereas the endometrial thickness does not seem to relate to the age.

摘要

目的

描述一组无症状绝经后妇女的盆腔器官超声参数及其与年龄相关的变化,并描述斯里兰卡人群中超声检测到的病变的患病率。

研究设计

这是一项基于社区的大型纵向研究,使用从未使用过激素替代疗法的绝经后妇女的随机样本。

主要观察指标

国际子宫内膜肿瘤分析和国际卵巢肿瘤分析小组描述的盆腔超声检查中子宫、子宫内膜和卵巢的测量值。

结果

共接触了 815 名绝经后妇女,她们都自愿参加。这些妇女年龄在 45 至 74 岁之间,中位数(四分位距(IQR))为 62.0(10.0)岁。子宫体积中位数(IQR)为 18.1(17)ml,右侧和左侧卵巢体积中位数(IQR)分别为 17.3(22.9)ml 和 18.2(21.5)ml。子宫和卵巢体积均呈与年龄相关的下降(p<0.01)。此外,卵巢体积随体重指数的增加而增大(左侧 p<0.03,右侧 p<0.01)。人群中子宫内膜厚度的中位数(IQR)为 3.0(1.0)mm,未观察到与年龄相关的变化。61 名妇女的超声检测到妇科疾病,患病率为 7.5%(95%置信区间(CI)为 5.6-9.5)。

结论

本研究旨在描述斯里兰卡绝经后妇女的盆腔器官超声参数,为无症状绝经后妇女的子宫和卵巢体积提供参考值。子宫和卵巢体积均呈与年龄相关的下降,而子宫内膜厚度似乎与年龄无关。

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