Suppr超能文献

医生与药房购药行为和自我报告的处方阿片类药物滥用及误用之间的关联:一项调查研究。

The Association Between Doctor and Pharmacy Shopping and Self-Reported Misuse and Abuse of Prescription Opioids: A Survey Study.

作者信息

Stephenson Judith J, Cepeda M Soledad, Zhang Jie, Dinh Jade, Hall Kelsey, Esposito Daina B, Kern David M

机构信息

Scientific Affairs, HealthCore, Inc, Wilmington, DE, USA.

Epidemiology, Janssen Research and Development, Titusville, NJ, USA.

出版信息

J Pain Res. 2020 Apr 3;13:689-701. doi: 10.2147/JPR.S232409. eCollection 2020.

Abstract

BACKGROUND/RATIONALE: Little is known about the reasons for visiting multiple doctors/pharmacies, known as doctor/pharmacy shopping, to obtain opioids.

OBJECTIVE

To investigate patients' self-reported reasons for doctor/pharmacy shopping and assess whether doctor/pharmacy shopping behavior can be used as a surrogate measure of opioid abuse/misuse.

METHODS

We conducted a cross-sectional web-based survey among adult patients with ≥2 pharmacy claims for immediate-release or extended-release/long-acting opioids between 7/1/2015 and 12/31/2016, identified from a large United States (US) commercial claims database. Patients were classified into no, mild, moderate, or severe shopping categories based on their claims. Reasons for doctor/pharmacy shopping and opioid abuse/misuse were determined from patient responses to the Prescription Opioid Misuse and Abuse Questionnaire.

RESULTS

A random sample of 10,081 patients was invited to participate in the survey and 1085 (11%) completed surveys. The most frequently reported reasons for doctor/pharmacy shopping were convenience, availability, price, and multiple morbidities requiring pain management. Among patients in the no, minimal, moderate, and severe shopping categories, only 7.8%, 8.5%, 11.8% and 12.6% reported opioid abuse/misuse, respectively.

CONCLUSION

In this commercially-insured population, patient-reported reasons for doctor/pharmacy shopping do not suggest opioid abuse/misuse. Less than 15% of patients with shopping behavior in the past 3 months reported any reasons attributable to opioid abuse/misuse, indicating that shopping behavior in this population may not be a good surrogate for abuse/misuse.

摘要

背景/基本原理:对于为获取阿片类药物而拜访多位医生/药店(即所谓的“医生/药店购物”行为)的原因,我们知之甚少。

目的

调查患者自述的医生/药店购物原因,并评估医生/药店购物行为是否可作为阿片类药物滥用/误用的替代指标。

方法

我们从美国一个大型商业理赔数据库中识别出在2015年7月1日至2016年12月31日期间有≥2次速释或缓释/长效阿片类药物药店理赔记录的成年患者,开展了一项基于网络的横断面调查。根据患者的理赔记录,将其分为无、轻度、中度或重度购物类别。通过患者对处方阿片类药物滥用和误用问卷的回答,确定医生/药店购物原因以及阿片类药物滥用/误用情况。

结果

随机抽取10,081名患者邀请其参与调查,1085名(11%)患者完成了调查。最常报告的医生/药店购物原因是便利性、可获取性、价格以及多种疾病需要疼痛管理。在无、轻度、中度和重度购物类别患者中,分别只有7.8%、8.5%、11.8%和12.6%的患者报告有阿片类药物滥用/误用情况。

结论

在这个商业保险人群中,患者自述的医生/药店购物原因并不表明存在阿片类药物滥用/误用。在过去3个月有购物行为的患者中,不到15%的患者报告了任何可归因于阿片类药物滥用/误用的原因,这表明该人群中的购物行为可能不是滥用/误用的良好替代指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7267/7140905/2ba4f6d9002e/JPR-13-689-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验