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慢性淋巴细胞白血病合并自身免疫性溶血性贫血患者的铁过载:一例报告

Iron Overload in Patients with Chronic Lymphocytic Leukemia Complicated by Autoimmune Hemolytic Anemia: A Case Report.

作者信息

Ali Mohammad, Yassin Mohamed A

机构信息

Department of Medical Education, Hamad Medical Corporation, Doha, Qatar.

Department of Medical Oncology, Hematology Section, National Center for Cancer Care & Research, Hamad Medical Corporation, Doha, Qatar.

出版信息

Case Rep Oncol. 2020 Mar 16;13(1):219-224. doi: 10.1159/000506472. eCollection 2020 Jan-Apr.

Abstract

Iron overload is commonly seen in the context of hematological diseases in patients who require frequent transfusions. On the other hand, an association between autoimmune hemolytic anemia complicating chronic lymphocytic leukemia and iron overload is unusual. Here, we report 2 cases of iron overload in patients with a background of chronic lymphocytic leukemia complicated by autoimmune hemolytic anemia. Both patients were found to have a high liver iron concentration on liver MRI (FerriScan). This observation raises the important question about the value of screening for iron overload in this group of patients.

摘要

铁过载在需要频繁输血的血液系统疾病患者中很常见。另一方面,自身免疫性溶血性贫血并发慢性淋巴细胞白血病与铁过载之间的关联并不常见。在此,我们报告2例有慢性淋巴细胞白血病背景且并发自身免疫性溶血性贫血的患者出现铁过载的病例。两名患者在肝脏MRI(FerriScan)检查中均发现肝脏铁浓度较高。这一观察结果引发了关于对该组患者进行铁过载筛查价值的重要问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0808/7154280/bd414b191bea/cro-0013-0219-g01.jpg

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