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经导管动脉化疗栓塞术治疗外阴癌:一例报告

Transcatheter Arterial Chemoembolization Treatment for Vulvar Cancer: A Case Report.

作者信息

Zhao Baokui, Xue Hui

机构信息

Department of Radiology Imaging and Intervention, Red Cross Hospital of Qinghai, Xining, China.

Department of Oncology, Red Cross Hospital of Qinghai, Xining, China.

出版信息

Case Rep Oncol. 2020 Mar 24;13(1):285-290. doi: 10.1159/000506471. eCollection 2020 Jan-Apr.

Abstract

Vulvar cancer is a rare malignant tumor occurring in elderly postmenopausal women. At present, surgery is the main treatment for vulvar cancer. Chemotherapy alone has no obvious therapeutic effect as a treatment for vulvar cancer, so it is often combined with radiotherapy or surgery. Selective arterial infusion chemotherapy and embolization is rarely used for the treatment of vulvar cancer. A 63-year-old Tibetan woman underwent superselective arteriography and embolization. On the 7th day after the operation, the vulvar tumor was necrotic and fell off, and a skin defect at the left labia majora appeared. This patient had no other serious complications. Arterial embolization can block the blood supply to a vulvar tumor, has an obvious effect in reducing the tumor, and can even induce tumor necrosis and make the tumor fall off. However, the skin defect after necrosis and abscission does not heal easily, and even carries the risk of local bleeding, which should be paid attention to by the interventionalist and oncologist. The clinical effects of transcatheter arterial embolization for vulvar cancer still need to be studied by interventionalists and oncologists.

摘要

外阴癌是一种发生于绝经后老年女性的罕见恶性肿瘤。目前,手术是外阴癌的主要治疗方法。单纯化疗作为外阴癌的治疗手段并无明显疗效,因此常与放疗或手术联合使用。选择性动脉灌注化疗和栓塞术很少用于外阴癌的治疗。一名63岁的藏族女性接受了超选择性动脉造影和栓塞术。术后第7天,外阴肿瘤坏死脱落,左侧大阴唇出现皮肤缺损。该患者无其他严重并发症。动脉栓塞可阻断外阴肿瘤的血供,在缩小肿瘤方面有明显效果,甚至可诱导肿瘤坏死并使肿瘤脱落。然而,坏死脱落后的皮肤缺损不易愈合,甚至存在局部出血风险,介入科医生和肿瘤内科医生应予以关注。经导管动脉栓塞术治疗外阴癌的临床效果仍需介入科医生和肿瘤内科医生进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deb0/7154278/f3f92811bfce/cro-0013-0285-g01.jpg

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