Schumacher David, Schuh Alexander
Department of Anesthesiology, University Hospital, RWTH Aachen, Germany.
Department of Cardiology and Pulmonology, Medical Faculty, RWTH Aachen University, Germany.
Discoveries (Craiova). 2019 Sep 30;7(3):e97. doi: 10.15190/d.2019.10.
Fibroblast Growth Factor 23 (FGF23) is a hormone involved in phosphate metabolism. It is known that FGF23 is increased in different pathologies including chronic kidney disease, heart failure or X-linked hypophosphatemia and directly correlates with negative outcome and mortality in severe diseases. However, the role of FGF23 in cardiovascular pathologies is still under debate. This review summarizes the current knowledge about the role of FGF23 in ischemic heart diseases, such as myocardial infarction.
成纤维细胞生长因子23（FGF23）是一种参与磷酸盐代谢的激素。已知FGF23在包括慢性肾病、心力衰竭或X连锁低磷血症在内的不同病理状态下会升高，并且与严重疾病的不良结局和死亡率直接相关。然而，FGF23在心血管疾病中的作用仍存在争议。本综述总结了目前关于FGF23在缺血性心脏病（如心肌梗死）中作用的相关知识。
