Mora Paolo, Calzetti Giacomo, Avellis Fernando O, Tedesco Salvatore A, Carta Arturo, Gandolfi Stefano, Zografos Leonidas
Ophthalmology Unit, University Hospital of Parma, Parma, Italy.
"Jules Gonin" Eye Hospital, University of Lausanne, Lausanne, Switzerland.
Am J Ophthalmol Case Rep. 2020 Apr 8;18:100685. doi: 10.1016/j.ajoc.2020.100685. eCollection 2020 Jun.
To report, with the aid of original imaging, an unusual differential diagnosis of an iris tumor.
A 60-year-old Caucasian man visited our clinic with a large amelanotic iris mass in the left eye in the absence of concomitant extraocular inflammation or neoplastic evidence. The patient reported an ocular trauma caused by a wire 5 years prior to his visit, which resolved after a short course of antibiotic eye drops. Orbital magnetic resonance imaging with contrast enhancement was consistent with an iris tumor; ultrasound biomicroscopy indicated a semi-solid, mid-stromal iris formation continuous with the lens. Surgical inspection was performed. Surgery showed the presence of a hypermature cataract with a fine break in the anterior capsule of the lens covered by the iris surface. The liquefied cortex infiltrated the iris without diffusing into the aqueous humor.
A so-called morgagnian cataract developed, likely following a penetrating ocular wound. The progressive, slow infiltration of the iris stroma by the crystalline matrix mimicked the appearance of an amelanotic iris tumor.