Wang Hao, Gao Yuzhen, Zhou Chunlin, Li Gang
Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, State Key Laboratory of Structural Chemistry, Center for Excellence in Molecular Synthesis, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, Fujian, China.
Fujian College, University of Chinese Academy of Sciences, Beijing 100049, China.
J Am Chem Soc. 2020 May 6;142(18):8122-8129. doi: 10.1021/jacs.0c03144. Epub 2020 Apr 24.
The first example of visible-light-driven reductive carboarylation of styrenes with CO and aryl halides in a regioselective manner has been achieved. A broad range of aryl iodides and bromides were compatible with this reaction. Moreover, pyridyl halides, alkyl halides, and even aryl chlorides were also viable with this method. These findings may stimulate the exploration of novel visible-light-driven Meerwein arylation-addition reactions with user-friendly aryl halides as the radical sources and the photocatalytic utilization of CO.
已实现首例以区域选择性方式通过可见光驱动苯乙烯与CO和芳基卤化物进行还原碳芳基化反应。多种芳基碘化物和溴化物与该反应兼容。此外，吡啶基卤化物、烷基卤化物甚至芳基氯化物也适用于此方法。这些发现可能会激发对新型可见光驱动的Meerwein芳基化加成反应的探索，该反应使用对用户友好的芳基卤化物作为自由基源并对CO进行光催化利用。
