Shanghai Key Laboratory of Brain Functional Genomics, Key Laboratory of Brain Functional Genomics Ministry of Education, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.
Program of Brain and Cognitive Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Elife. 2020 Apr 20;9:e54519. doi: 10.7554/eLife.54519.
Humans recall the past by replaying fragments of events temporally. Here, we demonstrate a similar effect in macaques. We trained six rhesus monkeys with a temporal-order judgement (TOJ) task and collected 5000 TOJ trials. In each trial, the monkeys watched a naturalistic video of about 10 s comprising two across-context clips, and after a 2 s delay, performed TOJ between two frames from the video. The data are suggestive of a non-linear, time-compressed forward memory replay mechanism in the macaque. In contrast with humans, such compression of replay is, however, not sophisticated enough to allow these monkeys to skip over irrelevant information by compressing the encoded video globally. We also reveal that the monkeys detect event contextual boundaries, and that such detection facilitates recall by increasing the rate of information accumulation. Demonstration of a time-compressed, forward replay-like pattern in the macaque provides insights into the evolution of episodic memory in our lineage.
人类通过回放事件片段来回忆过去。在这里，我们在猕猴中证明了类似的效应。我们用时间顺序判断（TOJ）任务训练了六只猕猴，并收集了 5000 次 TOJ 试验。在每次试验中，猴子观看大约 10 秒的自然主义视频，包括两个跨上下文的片段，然后在 2 秒的延迟后，在视频的两个帧之间进行 TOJ。数据表明，猕猴中存在一种非线性、时间压缩的向前记忆重放机制。然而，与人类不同的是，这种重放的压缩还不够复杂，无法通过全局压缩编码视频来跳过无关信息。我们还揭示了猴子可以检测到事件上下文边界，并且这种检测可以通过增加信息积累的速度来促进回忆。在猕猴中展示的时间压缩、向前重放样模式为我们的谱系中情节记忆的进化提供了新的见解。
