Research, Rocky Mountain Regional Veterans Affairs Medical Center, Denver-Seattle Center of Innovation, 1700 North Wheeling Street, Aurora, CO 80045, USA; Division of Health Care Policy and Research, School of Medicine, University of Colorado, 1700 North Wheeling Street, Aurora, CO 80045, USA. Electronic address: https://twitter.com/cari_levy.
Research, Rocky Mountain Regional Veterans Affairs Medical Center, Denver-Seattle Center of Innovation, 1700 North Wheeling Street, Aurora, CO 80045, USA.
Med Clin North Am. 2020 May;104(3):471-489. doi: 10.1016/j.mcna.2020.01.004.
The purpose of this article is to present evidence on the efficacy and safety of medical cannabis as a therapy for symptom management in palliative care. This article provides an overview of the evidence on the risks and benefits of using medical cannabis for the indications of chronic pain, cancer-related pain, cancer cachexia, dementia, and Alzheimer's disease. Currently, there is insufficient evidence to determine the effectiveness and safety of cannabinoids for most reviewed indications, with the exception of chronic pain. Future research is required before palliative care clinicians can make evidence-based decisions on the integration of medical cannabis as adjunct therapies.
本文旨在提供医学大麻作为姑息治疗症状管理疗法的疗效和安全性证据。本文概述了使用医用大麻治疗慢性疼痛、癌痛、癌性恶病质、痴呆和阿尔茨海默病等适应症的风险和益处的证据。目前,除慢性疼痛外,大多数已审查适应症的大麻素有效性和安全性的证据还不够充分。姑息治疗临床医生在做出有关将医用大麻作为辅助治疗方法的循证决策之前,需要开展进一步的研究。