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在一家社区医院针对孕周≥35周出生的婴儿实施抗生素管理质量改进计划。

Implementation of an antibiotic stewardship quality improvement initiative in a community hospital for infants born at ≥35 weeks.

作者信息

Perez Eduardo M, Taylor Molly, Swanson Kristin, Laferney Jimmy D

机构信息

Division of Neonatology, Department of Pediatrics, Baylor Scott White Medical Center - FriscoFriscoTexas.

Pediatrix Medical Group of TexasDallasTexas.

出版信息

Proc (Bayl Univ Med Cent). 2019 Dec 23;33(2):188-190. doi: 10.1080/08998280.2019.1700725. eCollection 2020 Apr.

DOI:10.1080/08998280.2019.1700725
PMID:32313458
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7155974/
Abstract

We present our experience in the implementation of an antibiotic stewardship quality improvement initiative directed toward infants born at ≥35 weeks using as a primary tool the Kaiser Permanente early onset sepsis calculator (KP-EOS-C) at the Baylor Scott & White Medical Center - Frisco. After the approval and support of the medical staff and administration, we proceeded to launch an extensive educational program for all women's services nursing staff on how to utilize this calculator to communicate results to the pediatricians on staff. After implementation, we saw a 54% reduction in the number of infants undergoing sepsis workup evaluations and a 51% reduction in the number of infants receiving antibiotics ( < 0.001). We conclude that the implementation of this type of initiative may be feasible and worthwhile in other similar community hospitals, provided there is buy-in by physicians and administration as well as an extensive educational program to the hospital medical and nursing staff.

摘要

我们介绍了在贝勒·斯科特与怀特医疗中心 - 弗里斯科分院实施一项抗生素管理质量改进计划的经验,该计划针对孕周≥35周出生的婴儿,主要工具是凯撒医疗早期败血症计算器(KP-EOS-C)。在获得医务人员和管理层的批准与支持后,我们着手为所有妇产科护理人员开展一项广泛的教育项目,内容是如何使用这个计算器向在职儿科医生传达结果。实施后,我们发现接受败血症检查评估的婴儿数量减少了54%,接受抗生素治疗的婴儿数量减少了51%(<0.001)。我们得出结论,只要医生和管理层认可,并且为医院医护人员开展广泛的教育项目,在其他类似的社区医院实施这类计划可能是可行且值得的。

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本文引用的文献

1
Management of Neonates Born at ≥35 0/7 Weeks' Gestation With Suspected or Proven Early-Onset Bacterial Sepsis.胎龄≥35 周的疑似或确诊早发性细菌性败血症新生儿的处理。
Pediatrics. 2018 Dec;142(6). doi: 10.1542/peds.2018-2894.
2
Anti-microbial stewardship: antibiotic use in well-appearing term neonates born to mothers with chorioamnionitis.抗菌药物管理:患有绒毛膜羊膜炎的母亲所生的健康足月儿的抗生素使用情况
J Perinatol. 2017 Dec;37(12):1304-1309. doi: 10.1038/jp.2017.137. Epub 2017 Oct 5.
3
A Quantitative, Risk-Based Approach to the Management of Neonatal Early-Onset Sepsis.一种定量、基于风险的新生儿早发性败血症管理方法。
JAMA Pediatr. 2017 Apr 1;171(4):365-371. doi: 10.1001/jamapediatrics.2016.4678.
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Application of sepsis calculator in newborns with suspected infection.脓毒症计算器在疑似感染新生儿中的应用。
J Matern Fetal Neonatal Med. 2016 Dec;29(23):3860-5. doi: 10.3109/14767058.2016.1149563. Epub 2016 Mar 7.
5
Adverse consequences of neonatal antibiotic exposure.新生儿接触抗生素的不良后果。
Curr Opin Pediatr. 2016 Apr;28(2):141-9. doi: 10.1097/MOP.0000000000000338.
6
Defining neonatal sepsis.定义新生儿败血症。
Curr Opin Pediatr. 2016 Apr;28(2):135-40. doi: 10.1097/MOP.0000000000000315.
7
Early-onset neonatal sepsis.早发型新生儿败血症。
Clin Microbiol Rev. 2014 Jan;27(1):21-47. doi: 10.1128/CMR.00031-13.
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Management of neonates with suspected or proven early-onset bacterial sepsis.新生儿疑似或确诊早发性细菌败血症的处理。
Pediatrics. 2012 May;129(5):1006-15. doi: 10.1542/peds.2012-0541. Epub 2012 Apr 30.