Ahmed Talha
Internal Medicine, University of Maryland Medical Center, Baltimore, USA.
Cureus. 2020 Mar 19;12(3):e7323. doi: 10.7759/cureus.7323.
Heart failure with preserved ejection fraction (HFpEF) comprises half of the total heart failure (HF) population. It is a unique class of patients whose systolic heart function is preserved but have impaired diastolic function leading to symptoms typical of HF. In the era of 1980s and 1990s, 'congestive heart failure' was used to refer to all the HF patients. With a better understanding of pathophysiology of 'diastolic HF', the term 'HFpEF' got widespread acceptance in early 2000s. Despite the increasing awareness of pathophysiology and diagnostic modalities for this group of HF patients, it is unfortunate to say that the therapies that we can provide are limited when compared to their counterpart HF with reduced ejection fraction (HFrEF) group. This review will focus on the use of device therapy in patients with HFpEF, particularly implantable cardioverter defibrillator and cardiac resynchronization therapy.
射血分数保留的心力衰竭(HFpEF)占心力衰竭(HF)总人群的一半。这是一类独特的患者,其收缩期心脏功能保留,但舒张功能受损,导致出现典型的HF症状。在20世纪80年代和90年代,“充血性心力衰竭”用于指代所有HF患者。随着对“舒张性HF”病理生理学的更好理解,“HFpEF”一词在21世纪初得到广泛认可。尽管对这类HF患者的病理生理学和诊断方法的认识不断提高,但遗憾的是,与射血分数降低的HF(HFrEF)组相比,我们能提供的治疗方法有限。本综述将重点关注HFpEF患者的器械治疗,特别是植入式心脏复律除颤器和心脏再同步治疗。