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[Research progress on the expression and function of erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins in oral-related diseases].促红细胞生成素产生性肝细胞受体及其受体相互作用蛋白在口腔相关疾病中的表达与功能研究进展
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Apr 1;38(2):218-223. doi: 10.7518/hxkq.2020.02.018.
2
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[Regulatory Effects of Erythropoietin-producing Hepatocyte Kinase Receptor and Ephrin Ligand on Bone Remodeling].[促红细胞生成素产生肝细胞激酶受体和埃菲素配体对骨重塑的调节作用]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2018 Apr 28;40(2):294-298. doi: 10.3881/j.issn.1000-503X.2018.02.023.
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Role of the ephrin and Eph receptor tyrosine kinase families in angiogenesis and development of the cardiovascular system.ephrin和Eph受体酪氨酸激酶家族在血管生成及心血管系统发育中的作用。
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Dying to communicate: apoptotic functions of Eph/Ephrin proteins.濒死欲言:Eph/Ephrin 蛋白的凋亡功能。
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本文引用的文献

1
Ephrin-B2 reverse signaling regulates progression and lymph node metastasis of oral squamous cell carcinoma.Ephrin-B2反向信号传导调节口腔鳞状细胞癌的进展和淋巴结转移。
PLoS One. 2017 Nov 30;12(11):e0188965. doi: 10.1371/journal.pone.0188965. eCollection 2017.
2
Porphyromonas gingivalis lipopolysaccharide regulates ephrin/Eph signalling in human periodontal ligament fibroblasts.牙龈卟啉单胞菌脂多糖调节人牙周膜成纤维细胞中的 Ephrin/Eph 信号通路。
J Periodontal Res. 2017 Oct;52(5):913-921. doi: 10.1111/jre.12463. Epub 2017 Jun 7.
3
Shear stress inhibits IL-17A-mediated induction of osteoclastogenesis via osteocyte pathways.剪切应力通过骨细胞途径抑制白细胞介素-17A介导的破骨细胞生成诱导。
Bone. 2017 Aug;101:10-20. doi: 10.1016/j.bone.2017.04.003. Epub 2017 Apr 14.
4
Disturbed Expression of EphB4, but Not EphrinB2, Inhibited Bone Regeneration in an In Vivo Inflammatory Microenvironment.EphB4而非EphrinB2的表达紊乱在体内炎症微环境中抑制骨再生。
Mediators Inflamm. 2016;2016:6430407. doi: 10.1155/2016/6430407. Epub 2016 Dec 18.
5
Low concentrations of TNF-α promote osteogenic differentiation via activation of the ephrinB2-EphB4 signalling pathway.低浓度的肿瘤坏死因子-α通过激活ephrinB2-EphB4信号通路促进成骨分化。
Cell Prolif. 2017 Feb;50(1). doi: 10.1111/cpr.12311. Epub 2016 Oct 11.
6
Ephrin-B2 overexpression predicts for poor prognosis and response to therapy in solid tumors.Ephrin-B2过表达预示实体瘤预后不良及对治疗的反应。
Mol Carcinog. 2017 Mar;56(3):1189-1196. doi: 10.1002/mc.22574. Epub 2016 Nov 1.
7
Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity.破骨细胞来源的含微小RNA的外泌体选择性抑制成骨细胞活性。
Cell Discov. 2016 May 31;2:16015. doi: 10.1038/celldisc.2016.15. eCollection 2016.
8
Effect of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) on the expression of EphA2 in osteoblasts and osteoclasts.牙龈卟啉单胞菌脂多糖(Pg-LPS)对成骨细胞和破骨细胞中EphA2表达的影响。
In Vitro Cell Dev Biol Anim. 2016 Feb;52(2):228-34. doi: 10.1007/s11626-015-9965-0. Epub 2015 Nov 11.
9
Crevicular alkaline phosphatase activity during the application of two patterns of orthodontic forces.两种正畸力施加模式下的龈沟碱性磷酸酶活性
J Orthod. 2015 Mar;42(1):5-13. doi: 10.1179/1465313314Y.0000000121.
10
Compression induces Ephrin-A2 in PDL fibroblasts via c-fos.压缩通过c-fos在牙周膜成纤维细胞中诱导Ephrin-A2。
J Dent Res. 2015 Mar;94(3):464-72. doi: 10.1177/0022034514567197. Epub 2015 Jan 20.

促红细胞生成素产生性肝细胞受体及其受体相互作用蛋白在口腔相关疾病中的表达与功能研究进展

[Research progress on the expression and function of erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins in oral-related diseases].

作者信息

Wang Qi, Liu Yan, Zhao Yun, Sun Li-Zhong, Wang Lin-Xuan, Han Mei, Mi Fang-Lin

机构信息

Dept. of Stomatology, North Sichuan Medical College, Nanchong 637000, China.

Dept. of Prosthodontics, the Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Apr 1;38(2):218-223. doi: 10.7518/hxkq.2020.02.018.

DOI:10.7518/hxkq.2020.02.018
PMID:32314898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7184288/
Abstract

Erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins (Eph/ephrin) can participate in the regulation of growth and development and promote the development of diseases through short-distance signal transduction between cells. To study the mechanism of Eph/ephrin and oral-related diseases, we provided a new theoretical basis and a strategy for the treatment of oral diseases. The Eph/ephrin pathway has been used to regulate oral diseases, especially in periodontal disease prevention, orthodontic bone reconstruction, and biological treatment of oral tumors. This paper reviews the research progress of Eph/ephrin pathway in oral-related diseases.

摘要

促红细胞生成素产生性肝细胞受体及其受体相互作用蛋白(Eph/ephrin)可通过细胞间短距离信号转导参与生长发育调控并促进疾病发展。为研究Eph/ephrin与口腔相关疾病的机制,我们为口腔疾病的治疗提供了新的理论基础和策略。Eph/ephrin通路已被用于调控口腔疾病,尤其是在牙周病预防、正畸骨重建及口腔肿瘤的生物治疗方面。本文综述了Eph/ephrin通路在口腔相关疾病中的研究进展。