Department of Pathology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Department of Pathology, G B Pant Institute of Postgraduate Medical Education and Research, New Delhi, India.
Indian J Pathol Microbiol. 2020 Apr-Jun;63(2):282-285. doi: 10.4103/IJPM.IJPM_289_19.
A 66-year-old male presented with chief complaints of anorexia associated with mild dull, intermittent epigastric pain for 6 months. The patient was a known diabetic on oral hypoglycemic and on routine checkup was found to have deranged liver function profile. On radiology, an ill-defined hypoechoic enhancing lesion involving head, neck, and uncinate process of pancreas was noted. Whipple's pancreaticodudenectomy was done and reported as IgG4-related autoimmune pancreatitis. Later, IgG (slightly) and IgG4 were found to be markedly raised. We report this case to highlight the importance of IgG4 evaluation prior to major surgery in uncertain pancreatic mass.
一位 66 岁男性,主要症状为食欲不振,伴有轻度间歇性隐痛,上腹疼痛 6 个月。该患者为已知糖尿病患者,口服降糖药,常规检查发现肝功能异常。影像学检查发现头部、颈部和胰钩突不规则低回声增强病变。行胰十二指肠 Whipple 切除术,报告为 IgG4 相关自身免疫性胰腺炎。后来发现 IgG(轻度)和 IgG4 明显升高。我们报告这个病例是为了强调在不确定的胰腺肿块行大手术前进行 IgG4 评估的重要性。