Kao Grace S, Bhandari Rashmi Parekh, Huestis Samantha E, Golianu Brenda
1Stanford Children's Health, Stanford University School of Medicine, Stanford, CA USA.
2Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA USA.
J Child Adolesc Trauma. 2017 Apr 17;11(2):249-255. doi: 10.1007/s40653-017-0145-0. eCollection 2018 Jun.
This theoretical review aims to present the limited findings on traumatic stress and pain in children and adolescents, highlight recent discoveries regarding neurobiological processes, and suggest an alternative stress-health perspective in the future study and conceptualization of pediatric pain and traumatic stress based on results. Current literature highlights a positive correlation between pain and trauma symptoms in youth and suggests a complex relationship that may have mutually maintaining dynamics and intertwined physiological processes. Developmentally sensitive, longitudinal, process-oriented designs assessing neurobiological alterations and stress responses should be utilized in the examination of the trauma-pain relationship. Such investigations may provide a more unified explanation of the relationship between chronic pain and traumatic stress.
本理论综述旨在呈现关于儿童和青少年创伤应激与疼痛的有限研究结果，强调近期有关神经生物学过程的发现，并基于研究结果，在未来儿科疼痛和创伤应激的研究及概念化方面提出一种替代性的应激 - 健康观点。当前文献强调了青少年疼痛与创伤症状之间的正相关关系，并表明这是一种复杂的关系，可能存在相互维持的动态变化和相互交织的生理过程。在研究创伤与疼痛的关系时，应采用对发育敏感、纵向、以过程为导向的设计来评估神经生物学改变和应激反应。此类研究可能会为慢性疼痛与创伤应激之间的关系提供更统一的解释。
