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腮腺皮脂腺淋巴腺瘤:1例免疫功能低下患者的独特表现病例报告

Sebaceous lymphadenoma of parotid gland: A case report of a unique presentation in an immunocompromised patient.

作者信息

Al-Essa Mohammed

机构信息

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Family Med Prim Care. 2020 Feb 28;9(2):1202-1205. doi: 10.4103/jfmpc.jfmpc_1115_19. eCollection 2020 Feb.

DOI:10.4103/jfmpc.jfmpc_1115_19
PMID:32318494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7114048/
Abstract

Sebaceous lymphadenoma is a rare, benign tumor of the parotid gland accounting for only 0.196% of all adenomas of the parotid gland. Our aim is to present a case of sebaceous lymphadenoma, which has been rapidly enlarging over a period of few months in an immunocompromised patient. This presentation is unusual for a benign salivary gland neoplasm. A 55-year-old female who is a known case of systemic lupus erythromatous, antiphospholipid syndrome, and lupus nephritis, which have been treated by cyclophosphamide, presented with a 2-year complaint of fluctuating painless right parotid swelling, over the last 3 months the swelling started to progressively increasing in size. Physical examination showed a 4 × 3 cm firm, nontender mass in the right parotid gland. The facial nerve was intact and no cervical lymphadenopathy. Fine-needle aspiration cytology (FNAC) revealed marked chronic inflammation and was not helpful for diagnosis. Right superficial parotidectomy was performed without complications and there was no recurrence after 24 months of careful follow-up. In patients presenting with a rapidly enlarging parotid mass associated with an intact facial nerve, the possibility of sebaceous lymphadenoma should be considered as an important differential diagnosis in addition to other benign tumors of the parotid gland. The role of FNAC in this neoplasm is controversial.

摘要

皮脂腺淋巴腺瘤是一种罕见的腮腺良性肿瘤,仅占腮腺所有腺瘤的0.196%。我们的目的是报告一例皮脂腺淋巴腺瘤病例,该病例在一名免疫功能低下的患者中在几个月内迅速增大。这种表现对于良性涎腺肿瘤来说并不常见。一名55岁女性,已知患有系统性红斑狼疮、抗磷脂综合征和狼疮性肾炎,曾接受环磷酰胺治疗,主诉右侧腮腺无痛性肿胀波动2年,在过去3个月中肿胀开始逐渐增大。体格检查显示右侧腮腺有一个4×3厘米的质地坚硬、无压痛的肿块。面神经完整,无颈部淋巴结肿大。细针穿刺细胞学检查(FNAC)显示有明显的慢性炎症,对诊断无帮助。行右侧腮腺浅叶切除术,无并发症,经过24个月的密切随访无复发。对于出现与面神经完整相关的迅速增大的腮腺肿块的患者,除了腮腺的其他良性肿瘤外,皮脂腺淋巴腺瘤的可能性应被视为重要的鉴别诊断。FNAC在这种肿瘤中的作用存在争议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/88171c8c01b9/JFMPC-9-1202-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/80de350c3540/JFMPC-9-1202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/1fce48207d81/JFMPC-9-1202-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/88171c8c01b9/JFMPC-9-1202-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/80de350c3540/JFMPC-9-1202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/1fce48207d81/JFMPC-9-1202-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f7e/7114048/88171c8c01b9/JFMPC-9-1202-g003.jpg

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