Sabino F, Bianco L, Cantoni V, Ghirardi P, Marchetti G V, Cicchetti V
Medical Department, Zambon Group, Milan, Italy.
Respiration. 1988;54 Suppl 1:114-9. doi: 10.1159/000195487.
A group of 36 patients with cor pulmonale chronicum were treated for 12 months with ibopamine, a dopamine-related drug, orally active, suitable for the long-term therapy of congestive heart failure. In heart failure due to chronic pulmonary disease other drugs such as digitalis are hardly effective. The results obtained indicate that ibopamine, given alone or associated to other drugs, is clinically efficient in the treatment of cor pulmonale chronicum while very few side effects definitely related to ibopamine were reported. In particular no increase in arrhythmias or significant augmentation of anginal episodes was noted.
一组36例慢性肺源性心脏病患者接受了异波帕明治疗,为期12个月。异波帕明是一种与多巴胺相关的药物,具有口服活性,适用于充血性心力衰竭的长期治疗。在慢性肺部疾病所致的心力衰竭中,洋地黄等其他药物疗效甚微。所获结果表明,单独使用异波帕明或与其他药物联用,在治疗慢性肺源性心脏病方面临床疗效显著,而明确与异波帕明相关的副作用报告极少。特别是未观察到心律失常增加或心绞痛发作显著增多。