Department of Dermatology, University of California, San Francisco, California.
Private Practice, West Orange, New Jersey.
J Am Acad Dermatol. 2020 Aug;83(2):463-468. doi: 10.1016/j.jaad.2020.04.042. Epub 2020 Apr 19.
Functional status assessment may help estimate which patients ≥85 years of age will benefit from surgical treatment for keratinocyte carcinoma (KC), but predictive value for short-term survival in this population has not been determined.
We sought to assess the predictive value of functional status for short-term survival in patients ≥85 years of age who have KC.
This was a retrospective cohort review of 238 patients ≥85 years of age who presented for the management of KC between 2010 and 2015. Functional status was assessed with the Karnofsky Performance Scale (KPS) and Katz Activities of Daily Living (ADL) index. Overall survival was determined.
Lower functional status scores of KPS ≤40 and Katz ADL ≤4 were associated with 37% and 53% survival at 2 years, respectively.
Retrospective design and single-center study.
In this study, KPS and Katz ADL predicted short-term survival. Patients with low functional status scores had significantly decreased survival at 2 years, with double the death rate of patients with high functional status. Functional status should be considered during shared decision-making for elderly individuals who are seeking treatment for KC.
功能状态评估可能有助于评估哪些 85 岁以上的患者将从手术治疗角质形成细胞癌 (KC) 中获益，但该人群短期生存的预测价值尚未确定。
我们旨在评估功能状态对患有 KC 的 85 岁以上患者短期生存的预测价值。
这是一项回顾性队列研究，共纳入 238 名 85 岁以上的患者，他们在 2010 年至 2015 年间因 KC 就诊。功能状态通过 Karnofsky 表现量表 (KPS) 和 Katz 日常生活活动 (ADL) 指数进行评估。确定总生存率。
KPS≤40 和 Katz ADL≤4 的较低功能状态评分分别与 2 年时 37%和 53%的生存率相关。
回顾性设计和单中心研究。
在这项研究中，KPS 和 Katz ADL 预测了短期生存。功能状态评分较低的患者在 2 年内的生存率显著降低，死亡率是功能状态较高患者的两倍。在为寻求 KC 治疗的老年个体进行共同决策时，应考虑功能状态。
