Campbell R B
Department of Mathematics and Computer Science, University of Northern Iowa, Cedar Falls 50614-0441.
Theor Popul Biol. 1988 Aug;34(1):24-37. doi: 10.1016/0040-5809(88)90033-0.
Probability of identity by type is studied for regular systems of inbreeding in the presence of mutation. Analytic results are presented for half-sib mating, first cousin mating, and half nth cousin mating under both infinite allele and two allele (back mutation) models. Reasonable rates of mutation do not provide significantly different results from probability of identity by descent in the absence of mutation. Homozygosity is higher under half-sib mating than under first cousin mating, but the expected number of copies of a gene in the population is higher under first cousin mating than under half-sib mating.
在存在突变的情况下，研究了近交常规系统中按类型的同一性概率。给出了在无限等位基因模型和两个等位基因（回突变）模型下，半同胞交配、一级表亲交配和半第n级表亲交配的分析结果。合理的突变率与无突变时按世系的同一性概率相比，不会产生显著不同的结果。半同胞交配下的纯合度高于一级表亲交配，但群体中一个基因的预期拷贝数在一级表亲交配下高于半同胞交配。
