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双子宫双腔双胎妊娠:一例报告

Uterine didelphys with dicavitary twin gestation: A case report.

作者信息

King Alison Laura, Pixton Sarah, Lanzarone Valeria

机构信息

Department of Obstetrics and Gynaecology, Nepean Hospital, Penrith, Australia.

出版信息

Case Rep Womens Health. 2020 Apr 3;27:e00199. doi: 10.1016/j.crwh.2020.e00199. eCollection 2020 Jul.

DOI:10.1016/j.crwh.2020.e00199
PMID:32322536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7163069/
Abstract

Uterine didelphys is a rare type of congenital uterine anomaly resulting from incomplete fusion of the paramesonephric ducts during embryogenesis. We report the case of a 27-year-old multiparous woman who presented with ovulation-induced dicavitary dichorionic diamniotic twins in known uterine didelphys. At 29 + 5 weeks of gestation, the patient had preterm prelabour rupture of membranes followed by threatened preterm labour in the right uterus only, which settled with tocolysis. The pregnancy continued for a further 9 days, at which time uterine tightenings returned and the right cervix was fully dilated, resulting in successful vaginal delivery of the first twin, leaving the placenta in situ. The left uterus and cervix remained quiescent for a further 24 h before contractions returned, resulting in emergency caesarean section, with the successful delivery of the second twin. As a rare phenomenon, there is sparse literature on the management of dicavitary twin gestation in uterine didelphys. This case report adds to the evidence for independent functioning of uteri and cervices in cases of uterine didelphys which may enable interval delivery delay in this cohort with known increased risk of preterm birth.

摘要

双子宫是一种罕见的先天性子宫畸形,由胚胎发育过程中副中肾管不完全融合所致。我们报告一例27岁经产妇,已知为双子宫,因促排卵出现双腔双绒毛膜双羊膜囊双胎妊娠。妊娠29 + 5周时,患者发生胎膜早破,随后仅右侧子宫出现先兆早产,经宫缩抑制剂治疗后缓解。妊娠又持续了9天,此时子宫收缩恢复,右侧宫颈完全扩张,成功经阴道分娩出第一个胎儿,胎盘未娩出。左侧子宫和宫颈在又平静了24小时后出现宫缩,行急诊剖宫产,成功娩出第二个胎儿。作为一种罕见现象,关于双子宫双腔双胎妊娠管理的文献较少。本病例报告为双子宫病例中子宫和宫颈独立功能的证据增添了内容,这可能使该早产风险已知增加的队列能够延迟间隔分娩。

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Uterine didelphys with dicavitary twin gestation: A case report.双子宫双腔双胎妊娠:一例报告
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Pan Afr Med J. 2023 Apr 28;44:205. doi: 10.11604/pamj.2023.44.205.39546. eCollection 2023.
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One patient with two uteri and two pregnancies - a rare case of twins in a patient with uterus didelphys.一位患者有两个子宫和两次妊娠——双子宫患者怀双胞胎的罕见病例。
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引用本文的文献

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Asynchronous twin delivery in uterus didelphys with a 12-week interval: case report and literature review.双子宫内间隔12周的异步双胎分娩:病例报告及文献综述
BMC Pregnancy Childbirth. 2025 Jul 9;25(1):736. doi: 10.1186/s12884-025-07865-w.
2
Di-Cavitary Twin Pregnancy in Didelphys Uterus with Associated Renal Agenesis.双子宫双腔双胎妊娠合并肾缺如
AJP Rep. 2025 Apr 10;15(2):e53-e57. doi: 10.1055/a-2562-1607. eCollection 2025 Apr.
3
Dicavitary twin pregnancy in patient with bicornuate bicollis uterine anomaly.双子宫双宫颈子宫畸形患者的双腔双胎妊娠
Clin Case Rep. 2023 Jun 7;11(6):e7440. doi: 10.1002/ccr3.7440. eCollection 2023 Jun.
4
The Impact of Uterus Didelphys on Fertility and Pregnancy.双子宫对生育和妊娠的影响。
Int J Environ Res Public Health. 2022 Aug 25;19(17):10571. doi: 10.3390/ijerph191710571.

本文引用的文献

1
A Case of Vaginal Birth after Cesarean Delivery in a Patient with Uterine Didelphys.双子宫患者剖宫产术后经阴道分娩1例。
Case Rep Obstet Gynecol. 2019 Dec 23;2019:3979581. doi: 10.1155/2019/3979581. eCollection 2019.
2
Twin gestation in a uterus didelphys with only one functional cervix: A case report.双子宫单功能性宫颈的双胎妊娠:一例报告。
Case Rep Womens Health. 2019 Apr 26;22:e00118. doi: 10.1016/j.crwh.2019.e00118. eCollection 2019 Apr.
3
Successful Vaginal Delivery of Naturally Conceived Dicavitary Twin in Didelphys Uterus: A Rare Reported Case.双子宫自然受孕双腔双胎成功经阴道分娩:一例罕见报道病例
Case Rep Obstet Gynecol. 2017;2017:7279548. doi: 10.1155/2017/7279548. Epub 2017 Aug 27.
4
Uterine Malformations: An Update of Diagnosis, Management, and Outcomes.子宫畸形:诊断、处理与结局的最新进展。
Obstet Gynecol Surv. 2017 Jun;72(6):377-392. doi: 10.1097/OGX.0000000000000444.
5
The association between obstetrical history and preterm birth in women with uterine anomalies.子宫异常女性的产科病史与早产之间的关联。
J Matern Fetal Neonatal Med. 2018 Oct;31(19):2550-2554. doi: 10.1080/14767058.2017.1347625. Epub 2017 Jul 9.
6
Uterine didelphys and vaginal birth after cesarean delivery.子宫中隔与剖宫产后阴道分娩。
Obstet Gynecol. 2015 Jan;125(1):157-159. doi: 10.1097/AOG.0000000000000505.
7
Comparison of the ESHRE-ESGE and ASRM classifications of Müllerian duct anomalies in everyday practice.日常实践中穆勒管异常的ESHRE-ESGE分类与ASRM分类的比较。
Hum Reprod. 2015 Mar;30(3):569-80. doi: 10.1093/humrep/deu344. Epub 2014 Dec 22.
8
Independent uterine contractions in simultaneous twin pregnancy in each horn of the uterus didelphys.双子宫双角同时双胎妊娠时的独立子宫收缩。
J Obstet Gynaecol Res. 2014 Mar;40(3):836-9. doi: 10.1111/jog.12219. Epub 2013 Nov 18.
9
Type of congenital uterine anomaly and adverse pregnancy outcomes.先天性子宫异常类型与不良妊娠结局。
J Matern Fetal Neonatal Med. 2014 Jun;27(9):949-53. doi: 10.3109/14767058.2013.847082. Epub 2013 Nov 26.
10
A case of spontaneous conceived twins in uterus didelphys, with induction and delayed delivery between twins.一例双子宫自然受孕双胞胎病例,双胞胎之间存在引产及分娩延迟情况。
J Obstet Gynaecol. 2013 Jul;33(5):525-6. doi: 10.3109/01443615.2013.792790.