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从药理学研究到药理学监管,再回归——受加夫里尔·帕斯特纳克博士教诲的启发

From Pharmacology Research, to Pharmacology Regulation, and Back-as Inspired by the Teachings of Dr. Gavril Pasternak.

作者信息

Luke Markham C

机构信息

Division of Therapeutic Performance, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.

出版信息

Cell Mol Neurobiol. 2021 Jul;41(5):835-837. doi: 10.1007/s10571-020-00837-y. Epub 2020 Apr 22.

Abstract

Dr. Gavril Pasternak, M.D., Ph.D. was an inspiration to many of his students, including myself. It was with great sadness that I learned about the passing of Dr. Gavril Pasternak in February 2019 after his brief battle with pancreatic cancer. I worked with Dr. Pasternak while I was an undergraduate chemistry student and as one of his technicians, collaborating with Dr. Charles Inturrisi and Dr. Eliot F. Hahn on opiate agonists and antagonists for opioid receptor subtypes. Dr. Pasternak inspired me and set me on the road to a career in pharmacology and encouraged me to pursue the fruitful paradigm of moving therapeutics from bench to bedside.

摘要

医学博士、哲学博士加夫里尔·帕斯特纳克医生激励了包括我在内的许多学生。得知加夫里尔·帕斯特纳克医生在与胰腺癌进行短暂抗争后于2019年2月去世,我深感悲痛。我在本科学习化学时以及作为他的一名技术人员时与帕斯特纳克医生共事,与查尔斯·因图里西医生和艾略特·F·哈恩医生合作研究阿片受体亚型的阿片类激动剂和拮抗剂。帕斯特纳克医生激励了我,让我走上了药理学的职业生涯道路,并鼓励我追求将治疗方法从实验室应用到临床的富有成效的模式。

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