Fubini S L, Cummings J F, Todhunter R J
Department of Clinical Sciences, New York State College of Veterinary Medicine, Ithaca 14853.
Vet Surg. 1988 Nov-Dec;17(6):346-9. doi: 10.1111/j.1532-950x.1988.tb01030.x.
Painful neuroma formation after palmar digital neurectomy in the horse is common. Experimentally, injection of doxorubicin (Adriamycin) into the proximal transected nerve stump has been shown to prevent axon sprouting and neuroma formation for up to 5 months. This procedure was used in 28 horses with navicular disease, preexisting painful neuroma, or wing fractures of the distal phalanx. At 1 month, 16 horses had incisional complications. At 1 year, 15 horses were sound. Eight horses were lame, although three were improved. Three horses required a second surgical procedure, two of which became sound. Follow-up was not available in two horses. The technique used in this study has an unacceptable rate of wound complications and no benefit over other palmar digital neurectomy techniques currently in use.
马匹掌部指神经切除术后形成疼痛性神经瘤很常见。实验表明，向近端切断的神经残端注射阿霉素（多柔比星）可在长达5个月的时间内防止轴突发芽和神经瘤形成。该手术应用于28匹患有舟状骨病、已有疼痛性神经瘤或远节指骨翼状骨折的马匹。1个月时，16匹马出现切口并发症。1年时，15匹马状况良好。8匹马跛行，不过有3匹有所改善。3匹马需要进行第二次手术，其中2匹术后状况良好。2匹马没有随访结果。本研究中使用的技术伤口并发症发生率不可接受，且与目前使用的其他掌部指神经切除术技术相比并无优势。
