Shahid Ashar, Punshi Avinash, Ahmed Khan Bilal, Nazir Maaz Bin, Ullah Hidayat
Internal Medicine, Dow University of Health Sciences (DUHS), Karachi, PAK.
Internal Medicine, Civil Hospital Karachi, Karachi, PAK.
Cureus. 2020 Mar 21;12(3):e7354. doi: 10.7759/cureus.7354.
Autoimmune hepatitis (AIH) is chronic inflammation of hepatocytes due to immune cells attacking the patient's own hepatocytes, histologically characterized by interface hepatitis. The disease can be serious, and if left untreated, it can lead to cirrhosis of the liver and eventual liver failure. It occurs more frequently in females. The standard treatment for AIH includes corticosteroids. There are two main treatment regimens, which include either prednisolone alone or prednisone and azathioprine. Although, liver transplantation is certainly the treatment of choice, it has not yet been established on a large scale worldwide. We present here the case of a 22-year-old male, with autoimmune hepatitis and unspecified vasculitis.
自身免疫性肝炎(AIH)是由于免疫细胞攻击患者自身肝细胞而导致的肝细胞慢性炎症,组织学特征为界面性肝炎。这种疾病可能很严重,如果不治疗,可能会导致肝硬化并最终发展为肝衰竭。它在女性中更为常见。AIH的标准治疗包括使用皮质类固醇。有两种主要的治疗方案,即单独使用泼尼松龙或泼尼松与硫唑嘌呤联合使用。尽管肝移植无疑是首选的治疗方法,但在全球范围内尚未大规模开展。我们在此介绍一名22岁男性患有自身免疫性肝炎和未明确的血管炎的病例。