[不同隐球菌属物种细胞外杂聚糖的结构]

[The structure of extracellular heteroglycans in various Cryptococcus species].

作者信息

Vitovskaia G, Samarkina G M, Anan'eva E P, Shashkov A S, Goncharov A Iu

出版信息

Bioorg Khim. 1988 Oct;14(10):1405-12.

Abstract

Extracellular polysaccharides produced by some Cryptococcus species have been structurally investigated. These polymers have identical core structure, which was found to be alpha-1,3-mannan and different degrees of substitution of mannose in the core by xylose and glucuronic acid residues of side chains and different composition of side chains. Heteropolysaccharide from Cr. humicolus, the simplest one, has the same structure as the Cr. neoformans serotype D capsular polysaccharide. The Cr. skinneri polymer proved to be the most branched among Cryptococcus polysaccharides.

摘要

一些隐球菌属物种产生的细胞外多糖已进行了结构研究。这些聚合物具有相同的核心结构，发现其为α-1,3-甘露聚糖，核心中的甘露糖被侧链的木糖和葡萄糖醛酸残基不同程度地取代，且侧链组成不同。来自土生隐球菌的杂多糖是最简单的一种，其结构与新型隐球菌D血清型荚膜多糖相同。斯氏隐球菌聚合物被证明是隐球菌多糖中分支最多的。