From the Department of Radiology, Mayo Clinic, Jacksonville.
Orange Park Medical Center, Orange Park, FL.
Clin Nucl Med. 2020 Jun;45(6):442-443. doi: 10.1097/RLU.0000000000003011.
Late recurrence of prostate cancer after remission with prior radical prostatectomy is uncommon. This is a unique case of biochemical recurrence after being in remission for 12 years. The patient presented with swelling of the right lower extremity with pelvic MRI demonstrating an arterially enhancing filling defect in the right common iliac. An F-fluciclovine PET/CT showed corresponding increased intravascular radiotracer activity. Targeted biopsy of the intravascular lesion showed poorly differentiated carcinoma, suggestive of prostate origin. Although MRI evaluation is the mainstay for pelvic evaluation, characterization with F-fluciclovine PET/CT imaging adds high whole-body specificity and diagnostic accuracy.
根治性前列腺切除术后缓解后前列腺癌的晚期复发并不常见。这是一个在缓解 12 年后发生生化复发的独特病例。患者出现右下肢肿胀，盆腔 MRI 显示右侧髂总动脉增强充盈缺损。F-氟代脱氧葡萄糖 PET/CT 显示相应的血管内放射性示踪剂活性增加。血管内病变的靶向活检显示分化差的癌，提示来源于前列腺。虽然 MRI 评估是盆腔评估的主要方法，但 F-氟代脱氧葡萄糖 PET/CT 成像的特征可提高全身特异性和诊断准确性。
