Barry L. Werth, PhD, Sydney Nursing School, University of Sydney, New South Wales, Australia.
Murray J. Fisher, PhD, Sydney Nursing School, University of Sydney, New South Wales, Australia.
J Wound Ostomy Continence Nurs. 2020 May/Jun;47(3):259-264. doi: 10.1097/WON.0000000000000632.
The aim of this study was to determine the prevalence of chronic constipation and identify factors associated with chronic constipation in community-dwelling adults.
Cross-sectional study.
The target population was community-dwelling Australian adults; 1978 participants completed an online questionnaire exploring symptoms, management, and factors potentially associated with constipation. Chronic constipation was identified using Rome III criteria. Multivariate logistic regression model was used to identify factors associated with chronic constipation.
The prevalence of chronic constipation was 23.9%. Factors significantly associated with chronic constipation in the multivariate model were female gender (odds ratio [OR] = 1.42, 95% confidence interval [CI], 1.12-1.81), current employment (OR = 1.45, 95% CI, 1.11-1.88), regular smoking (OR = 1.60, 95% CI, 1.19-2.14), poor self-rated health (OR = 2.57, 95% CI, 1.28-5.19), thyroid disease (OR = 1.77, 95% CI, 1.21-2.79), depression (OR = 1.49, 95% CI, 1.08-2.06), hemorrhoids (OR = 2.98, 95% CI, 1.84-4.83), irritable bowel syndrome (OR = 2.45, 95% CI, 1.73-3.46), and use of anti-inflammatory/antirheumatic medications (OR = 2.06, 95% CI, 1.15-3.68). In contrast to these factors, use of medications acting on the renin-angiotensin system was associated with a reduced likelihood of chronic constipation (OR = 0.47, 95% CI, 0.24-0.91).
Chronic constipation is prevalent among community-dwelling adults. Various factors associated with chronic constipation have been identified, and knowledge of these factors may help health care professionals recognize individuals who are at high risk of chronic constipation.
本研究旨在确定社区居民成年人慢性便秘的患病率，并确定与慢性便秘相关的因素。
横断面研究。
研究对象为社区居民的澳大利亚成年人；1978 名参与者完成了一份在线问卷，内容涉及症状、管理和可能与便秘相关的因素。使用罗马 III 标准确定慢性便秘。使用多变量逻辑回归模型确定与慢性便秘相关的因素。
慢性便秘的患病率为 23.9%。多变量模型中与慢性便秘显著相关的因素为女性（比值比 [OR] = 1.42，95%置信区间 [CI]，1.12-1.81）、当前就业（OR = 1.45，95%CI，1.11-1.88）、规律吸烟（OR = 1.60，95%CI，1.19-2.14）、自我健康评估差（OR = 2.57，95%CI，1.28-5.19）、甲状腺疾病（OR = 1.77，95%CI，1.21-2.79）、抑郁症（OR = 1.49，95%CI，1.08-2.06）、痔疮（OR = 2.98，95%CI，1.84-4.83）、肠易激综合征（OR = 2.45，95%CI，1.73-3.46）和使用抗炎/抗风湿药物（OR = 2.06，95%CI，1.15-3.68）。与这些因素相反，使用作用于肾素-血管紧张素系统的药物与慢性便秘的可能性降低相关（OR = 0.47，95%CI，0.24-0.91）。
慢性便秘在社区居民成年人中较为普遍。确定了与慢性便秘相关的各种因素，了解这些因素可能有助于医疗保健专业人员识别患有慢性便秘的高风险人群。
