Whelan Rachel, Soose Ryan J
Department of Otolaryngology, University of Pittsburgh School of Medicine, UPMC Mercy, University of Pittsburgh, Suite 2100, 1400 Locust Street, Pittsburgh, PA 15219, USA.
Division of Sleep Surgery, Department of Otolaryngology, University of Pittsburgh School of Medicine, UPMC Mercy, University of Pittsburgh, Suite 2100, 1400 Locust Street, Pittsburgh, PA 15219, USA.
Otolaryngol Clin North Am. 2020 Jun;53(3):445-457. doi: 10.1016/j.otc.2020.02.007. Epub 2020 Apr 23.
Hypoglossal nerve stimulation (HNS) therapy represents a novel approach and a paradigm shift in the evolution of obstructive sleep apnea (OSA) treatment as a hybrid surgically implanted, medically titratable device. Unlike traditional sleep apnea surgical procedures, HNS augments the neuromuscular activity of the pharynx, preserves upper airway structure and function, and has the potential to provide multilevel upper airway improvement with one procedure. The early success of HNS sets the stage for new technology development, further investigation into optimal patient selection and therapy titration, and application to other subsets of the OSA population.
舌下神经刺激（HNS）疗法是一种新型方法，也是阻塞性睡眠呼吸暂停（OSA）治疗发展过程中的一种范式转变，它是一种通过手术植入、可进行医学滴定的混合设备。与传统的睡眠呼吸暂停外科手术不同，HNS可增强咽部的神经肌肉活动，保留上呼吸道结构和功能，并有可能通过一次手术实现上呼吸道的多级改善。HNS的早期成功为新技术的开发、进一步研究最佳患者选择和治疗滴定以及应用于OSA人群的其他亚组奠定了基础。
