Sakata Masahiro, Egami Hideaki
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1, Shikatacho, Kitaku, Okayamashi, Okayama 700-8558, Japan; Gastroenterology and Hepatology, Fukuyama Medical Center, 4-14-17, Okinogami-cho, Fukuyama, Hiroshima, 720-8520, Japan.
Department of Innovative Kampo Medical Center, Kurume University Medical Center, 155-1, Kokubu-machi, Kurume, Fukuoka, 839-0863, Japan.
Explore (NY). 2021 Nov-Dec;17(6):521-524. doi: 10.1016/j.explore.2020.04.003. Epub 2020 Apr 19.
Pharmacologic treatment of dizziness is still not well-established. Consequently, traditional Japanese (Kampo) herbal medicine is commonly used. Ryokeijutsukanto is used to treat dizziness caused by orthostatic dysregulation (OD).
We aimed to evaluate the effectiveness of ryokeijutsukanto, a traditional Japanese (Kampo) herbal medicine, in treating dizziness, including light-headedness and/or palpitations. We focused on dizziness caused by OD, a condition commonly treated with ryokeijutsukanto.
We used a case series design.
The study was centered in the department of internal medicine and department of otolaryngology at a general hospital.
We tested ryokeijutsukanto in four female patients who were experiencing dizziness and who were diagnosed with OD.
INTERVENTION(S): The patients received ryokeijutsukanto (1.5 g to 4.2 g of dried extract daily).
MAIN OUTCOME MEASURE(S): Ryokeijutsukanto was prescribed to the four patients; clinical efficacy and improvement in dizziness were assessed using the Clinical Global Impression-Improvement scale and Vertigo Symptom Scale-Short Form.
All patients intended to continue Kampo treatment since high curative effects and no adverse effects were observed.
To the best of our knowledge, this is the first report elucidating the effectiveness of ryokeijutsukanto in treating dizziness as a result of OD. Ryokeijutsukanto may be an appropriate complementary therapy for OD.
头晕的药物治疗仍未完全确立。因此，传统的日本（汉方）草药经常被使用。苓桂术甘汤用于治疗由体位性调节障碍（OD）引起的头晕。
我们旨在评估传统日本（汉方）草药苓桂术甘汤治疗头晕（包括头晕和/或心悸）的有效性。我们重点关注由OD引起的头晕，这是一种常用苓桂术甘汤治疗的病症。
我们采用了病例系列设计。
该研究以一家综合医院的内科和耳鼻喉科为中心。
我们对四名经历头晕且被诊断为OD的女性患者进行了苓桂术甘汤测试。
患者服用苓桂术甘汤（每日1.5克至4.2克干提取物）。
对四名患者开了苓桂术甘汤；使用临床总体印象改善量表和眩晕症状量表简表评估临床疗效和头晕改善情况。
由于观察到高疗效且无不良反应，所有患者都打算继续汉方治疗。
据我们所知，这是第一份阐明苓桂术甘汤治疗OD所致头晕有效性的报告。苓桂术甘汤可能是OD的一种合适的辅助治疗方法。
