Younesian Hananeh, Farahpour Nader, Mazde Mehrdokht, Simoneau Martin, Turcot Katia
Laval University.
Center for Interdisciplinary Research in Rehabilitation and Social Integration (CIRRIS).
J Appl Biomech. 2020 Apr 25;36(3):171-177. doi: 10.1123/jab.2019-0365. Print 2020 Jun 1.
Diabetes peripheral neuropathy (DPN) leads to balance impairment among diabetes mellitus (DM). The aims of this study were to (1) distinguish between DM patients who have/do not have DPN and to (2) compare quadriceps' strength and balance performance of DM, DPN, and healthy groups. Fifteen healthy females and 33 females with type 2 diabetic patients participated. The electrodiagnostic method was used to classify diabetic patients into DM and DPN. A dynamometer was used to measure quadriceps' strength. Single-leg standing on a force plate was also used to quantify participants' balance. Smaller conduction velocity and amplitude and greater distal latency of all nerves were observed in the DPN compared with the DM in particular for sensory nerve. In DPN, conduction velocity was asymmetrical. The quadriceps' strength of both legs in DPN and the right leg in DM was smaller than in the control group. The root mean square of the center of pressure was similar between DM and DPN. But it was larger in DPN than in the control group. DPN is associated with asymmetrical conduction velocity, smaller quadriceps' strength, and weaker balance performance that is suggestive of higher risk of falling. Balance training is recommended for the DPN group during their rehabilitation to reduce their falling risk.
糖尿病周围神经病变（DPN）会导致糖尿病（DM）患者出现平衡功能受损。本研究的目的是：（1）区分患有/未患有DPN的DM患者；（2）比较DM组、DPN组和健康组的股四头肌力量及平衡能力。15名健康女性和33名2型糖尿病女性患者参与了研究。采用电诊断方法将糖尿病患者分为DM组和DPN组。使用测力计测量股四头肌力量。还采用在测力板上单腿站立的方式来量化参与者的平衡能力。与DM组相比，DPN组所有神经的传导速度和波幅更小，尤其是感觉神经的远端潜伏期更长。在DPN组中，传导速度不对称。DPN组双腿以及DM组右侧腿的股四头肌力量均小于对照组。DM组和DPN组的压力中心均方根相似，但DPN组的该指标大于对照组。DPN与传导速度不对称、股四头肌力量较小以及平衡能力较弱相关，这表明跌倒风险较高。建议DPN组在康复期间进行平衡训练以降低跌倒风险。
