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重症监护病房脓毒症的情况。

Scenario of Sepsis in Intensive Care Unit in a Tertiary Care Hospital.

机构信息

Department of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar.

Department of Biochemistry, Nobel Medical College Teaching Hospital, Biratnagar.

出版信息

J Nepal Health Res Counc. 2020 Apr 20;18(1):99-102. doi: 10.33314/jnhrc.v18i1.2498.

DOI:10.33314/jnhrc.v18i1.2498
PMID:32335601
Abstract

BACKGROUND

Sepsis has been defined as life-threatening organ dysfunction caused by dysregulated host response to infection. Sepsis is an important cause of mortality in intensive care unit worldwide. The study aims to identify the outcome of sepsis patient admitted at tertiary care hospital.

METHODS

This is a descriptive cross-sectional hospital based study on 76 adult patients admitted at intensive care unit of Nobel Medical College with diagnosis of sepsis with an objective of estimating mortality of sepsis and identifying associated symptoms with it. Baseline demographics, clinical and laboratory data were collected and analyzed.

RESULTS

Out of 76 patients with sepsis, mean age of the patients was 50.07±18.15 years. Majority of patients 31.6% with sepsis were above age groups >60 years. The most common symptoms among the patients were fever, which was seen in 69 (90.8%) patients. The most common source of infection in those patients was found to be unknown, which was seen in 36.8% of patients. While analyzing the outcome, it was noted that 25 patients with sepsis (32.9%) died during treatment.

CONCLUSIONS

Sepsis is related with high mortality. Elderly patients are at more risk. Fever is the commonest presentation and source is not identified in majority of cases.

摘要

背景

败血症被定义为感染引起的宿主反应失调导致的危及生命的器官功能障碍。败血症是全球重症监护病房死亡的重要原因。本研究旨在确定在三级保健医院住院的败血症患者的结局。

方法

这是一项在诺贝尔医学院重症监护病房住院的 76 例成人败血症患者的描述性横断面医院研究,目的是估计败血症的死亡率并确定与其相关的症状。收集并分析了基线人口统计学、临床和实验室数据。

结果

在 76 例败血症患者中,患者的平均年龄为 50.07±18.15 岁。年龄>60 岁的患者中,有 31.6%患有败血症。在这些患者中,最常见的症状是发热,69 例(90.8%)患者有发热。在这些患者中,最常见的感染源是未知的,占 36.8%的患者。在分析结局时,注意到 25 例败血症(32.9%)患者在治疗期间死亡。

结论

败血症与高死亡率有关。老年患者风险更高。发热是最常见的表现,大多数情况下无法确定病因。

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