针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的免疫球蛋白G和IgM抗体概况
Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
作者信息
Qu Jiuxin, Wu Chi, Li Xiaoyong, Zhang Guobin, Jiang Zhaofang, Li Xiaohe, Zhu Qing, Liu Lei
机构信息
Department of Clinical Laboratory, The Third People's Hospital of Shenzhen, Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases, Shenzhen, China.
Department of Infectious Diseases, The Third People's Hospital of Shenzhen, Southern University of Science and Technology, National Clinical Research Center for Infectious Diseases, Shenzhen, China.
出版信息
Clin Infect Dis. 2020 Nov 19;71(16):2255-2258. doi: 10.1093/cid/ciaa489.
Abstract
We profiled the serological responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger, antibody responses were observed in critical patients.
摘要
我们分析了对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）核衣壳（N）蛋白和刺突（S）糖蛋白的血清学反应。大多数患者在发病后17至23天之间产生了强烈的抗体反应。在重症患者中观察到抗体反应延迟但更强。
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