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上胸椎硬膜内髓外转移瘤——病例报告及文献综述

Intradural Extramedullary Metastasis of the Upper Thoracic Spine – Case Report and Literature Review.

作者信息

Kehayov Ivo, Genova Sylvia, Gicheva Maria, Nuri Bahar, Kitov Borislav

机构信息

Medical University of Plovdiv, Plovdiv, Bulgaria.

St George University Hospital, Plovdiv, Bulgaria.

出版信息

Folia Med (Plovdiv). 2019 Dec 31;61(4):624-629. doi: 10.3897/folmed.61.e47948.

DOI:10.3897/folmed.61.e47948
PMID:32337876
Abstract

We report a case of 46-year-old male operated on for moderately differentiated lung adenocarcinoma. Postoperatively, he underwent six courses of chemotherapy and radiotherapy. He developed progressive severe inferior paraparesis accompanied by excruciating pain between the shoulders two years later. Magnetic resonance imaging revealed metastases in the bodies of T2 and T3 vertebrae with adjacent intradural extramedullary lesion compressing the spinal cord. The patient underwent surgical decompression and vertebral body cement augmentation that lead to pain relief and partial neurological recovery. The histological examination was consistent with metastases from low differentiated pulmonary adenocarcinoma. Surgical resection of intradural extramedullary metastasis improves patient quality of life by reducing pain intensity and neurological deficit.

摘要

我们报告一例46岁男性因中度分化肺腺癌接受手术治疗。术后,他接受了六个疗程的化疗和放疗。两年后,他出现进行性严重下肢轻瘫,并伴有肩部之间难以忍受的疼痛。磁共振成像显示T2和T3椎体转移,伴有相邻的硬膜内髓外病变压迫脊髓。患者接受了手术减压和椎体骨水泥强化,疼痛缓解,神经功能部分恢复。组织学检查与低分化肺腺癌转移相符。硬膜内髓外转移瘤的手术切除通过减轻疼痛强度和神经功能缺损改善了患者的生活质量。

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