Tibbo Meagan E, Brown Timothy S, Hanssen Arlen D, Lewallen David G, Sim Franklin H, Abdel Matthew P
Department of Orthopaedic Surgery, Mayo Clinic, Rochester, MN, USA.
University of Iowa Hospitals and Clinics, Iowa, UK.
Hip Int. 2022 Jan;32(1):67-72. doi: 10.1177/1120700020920178. Epub 2020 Apr 28.
Paget's disease affects 3-4% of the population; however, literature describing outcomes of total hip arthroplasty (THA) in this population are limited. Given the known concerns with bleeding, heterotopic ossification (HO), and component loosening, we describe our results with primary and revision THAs in Paget's disease with emphasis on implant survivorship, radiographic results, and clinical outcomes.
We identified 25 THAs performed with contemporary uncemented acetabular components in patients with Paget's disease from 1999 to 2014. Mean age and follow-up were 78 and 7 years.
In primary THAs, survivorship free from aseptic acetabular and femoral loosening was 100% and 94% at 8 years. 7 patients (41%) received blood transfusions. HO was seen in 9 (53%). Mean Harris Hip Score (HHS) improved from 49 to 76. In revision THAs, survivorship free from acetabular and/or femoral aseptic loosening was 100% at 5 years. 3 patients (38%) received a transfusion. HO was seen in 5 (63%). Mean HHS improved from 52 to 77. There were no radiographic signs of aseptic loosening among unrevised cases in either group.
Our investigation demonstrates that concerns with acetabular fixation in Paget's disease have been mitigated with contemporary uncemented acetabular components. Complications previously noted, namely intraoperative bleeding and HO, continue to be of concern.
佩吉特病影响3% - 4%的人群;然而,描述该人群全髋关节置换术(THA)结果的文献有限。鉴于已知的出血、异位骨化(HO)和假体松动问题,我们描述了佩吉特病初次和翻修THA的结果,重点关注假体生存率、影像学结果和临床结局。
我们确定了1999年至2014年期间对患有佩吉特病的患者进行的25例使用当代非骨水泥髋臼组件的THA手术。平均年龄和随访时间分别为78岁和7年。
在初次THA中,8年时无菌性髋臼和股骨假体松动的生存率分别为100%和94%。7例患者(41%)接受了输血。9例(53%)出现HO。平均Harris髋关节评分(HHS)从49分提高到76分。在翻修THA中,5年时髋臼和/或股骨无菌性松动的生存率为100%。3例患者(38%)接受了输血。5例(63%)出现HO。平均HHS从52分提高到77分。两组未翻修病例中均无无菌性松动的影像学迹象。
我们的研究表明,当代非骨水泥髋臼组件已减轻了对佩吉特病髋臼固定的担忧。先前指出的并发症,即术中出血和HO,仍然令人担忧。