Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Southern Illinois University, Springfield, Illinois, USA.
Otolaryngol Head Neck Surg. 2020 Jul;163(1):16-24. doi: 10.1177/0194599820923623. Epub 2020 Apr 28.
Due to the current coronavirus disease 2019 (COVID-19) pandemic, otolaryngologists face novel challenges when treating patients with head and neck cancer. The purpose of this review is to evaluate the current evidence surrounding the treatment of these patients during this pandemic and to provide evidence-based recommendations with attention to increased risk in this setting.
A review of the literature was performed with PubMed. Because recently published articles on this topic may not yet be indexed into PubMed, otolaryngology journals were hand searched for relevant articles. Guidelines from national organizations were reviewed to identify additional relevant sources of information.
Two groups of search terms were created: one with terms related to COVID-19 and another with terms related to head and neck cancer and its management. Searches were performed of all terms in each group as well as combinations of terms between groups. Searches and subsequent exclusion of articles were performed in accordance with the PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-analyses). Additional articles were identified after relevant journals and guidelines from national organizations were reviewed.
Patients with head and neck mucosal malignancy require continued treatment despite the current pandemic state. Care must be taken at all stages of treatment to minimize the risk to patients and health care workers while maintaining focus on minimizing use of limited resources.
Patient care plans should be guided by best available evidence to optimize outcomes while maintaining a safe environment in the setting of this pandemic.
由于当前的 2019 年冠状病毒病（COVID-19）大流行，耳鼻喉科医生在治疗头颈部癌症患者时面临新的挑战。本综述的目的是评估当前在大流行期间治疗这些患者的证据，并提供循证建议，同时关注该环境下的风险增加。
通过 PubMed 进行文献综述。由于最近发表的关于该主题的文章可能尚未被索引到 PubMed 中，因此对手头的耳鼻喉科杂志进行了检索，以查找相关文章。审查了来自国家组织的指南，以确定其他相关信息来源。
创建了两组搜索词：一组与 COVID-19 相关，另一组与头颈部癌症及其管理相关。对每组中的所有术语以及两组之间的术语组合进行了搜索和随后的文章排除。根据 PRISMA 指南（系统评价和荟萃分析的首选报告项目）进行了搜索和随后的文章排除。在审查了相关期刊和来自国家组织的指南后，确定了其他文章。
尽管目前处于大流行状态，但仍需要继续对头颈部黏膜恶性肿瘤患者进行治疗。在治疗的所有阶段都必须谨慎行事，以最大程度地降低患者和医护人员的风险，同时专注于最大限度地减少有限资源的使用。
应根据最佳现有证据制定患者护理计划，以在大流行环境中优化结果，同时保持安全的环境。
