Universiti Sains Malaysia, School of Medical Sciences, Department of Pathology, Health Campus, Kelantan, Malaysia.
Malays J Pathol. 2020 Apr;42(1):121-125.
Sarcomas of the Ewing family of tumours are aggressive neoplasms occurring in bone and soft tissue of mostly children and young adults. It usually affects male more than female with peak incidence 10 to 15 years of age, and rarely encountered in adults especially in more than 40 years old. It is an aggressive, rare tumour with a tendency toward recurrence after resection and early metastasis.
We reported a rare case of Ewing Sarcoma in a 62-year-old woman who had an unusual clinical presentation. She had right painless buttock swelling only for a month. Magnetic resonance imaging (MRI) revealed soft tissue sarcoma originated from right gluteal muscle. The diagnosis of Ewing sarcoma (ES) was made in a limited diagnostic material in an initial tru-cut biopsy, followed by an excision supported by immunohistochemistry (IHC) and Fluorescent In-Situ Hybridization (FISH).
The purpose of this study is to document ES in an adult woman and its diagnostic challenges in histopathologic perspective.
尤文氏家族肿瘤肉瘤是一种发生于骨骼和软组织的侵袭性肿瘤，主要见于儿童和青年。其发病通常男性多于女性，发病高峰在 10 至 15 岁，在成年人中很少见，特别是 40 岁以上人群中更为罕见。尤文肉瘤是一种侵袭性的罕见肿瘤，在切除后有复发和早期转移的倾向。
我们报告了一例罕见的 62 岁女性尤文肉瘤病例，其临床表现不典型。她仅在一个月前出现右侧臀部无痛性肿胀。磁共振成像（MRI）显示起源于右侧臀肌的软组织肉瘤。在初次 tru-cut 活检中，通过有限的诊断性材料确诊为尤文肉瘤（ES），随后通过免疫组织化学（IHC）和荧光原位杂交（FISH）支持的切除术进行确诊。
本研究旨在记录一名成年女性的尤文肉瘤，并从组织病理学角度探讨其诊断挑战。
